Sleep in Drosophila and Its Context

EJ Beckwith, AS French - Frontiers in physiology, 2019 - frontiersin.org
A prominent idea emerging from the study of sleep is that this key behavioural state is
regulated in a complex fashion by ecologically and physiologically relevant environmental …

Chronic social isolation signals starvation and reduces sleep in Drosophila

W Li, Z Wang, S Syed, C Lyu, S Lincoln, J O'Neil… - Nature, 2021 - nature.com
Social isolation and loneliness have potent effects on public health,,–. Research in social
psychology suggests that compromised sleep quality is a key factor that links persistent …

Hitting the right note at the right time: Circadian control of audibility in Anopheles mosquito mating swarms is mediated by flight tones

J Somers, M Georgiades, MP Su, J Bagi, M Andrés… - Science …, 2022 - science.org
Mating swarms of malaria mosquitoes form every day at sunset throughout the tropical
world. They typically last less than 30 minutes. Activity must thus be highly synchronized …

Neuronal identity defines α-synuclein and tau toxicity

R Praschberger, S Kuenen, N Schoovaerts, N Kaempf… - Neuron, 2023 - cell.com
Pathogenic α-synuclein and tau are critical drivers of neurodegeneration, and their
mutations cause neuronal loss in patients. Whether the underlying preferential neuronal …

Sensory processing during sleep in Drosophila melanogaster

AS French, Q Geissmann, EJ Beckwith, GF Gilestro - Nature, 2021 - nature.com
During sleep, most animal species enter a state of reduced consciousness characterized by
a marked sensory disconnect. Yet some processing of the external world must remain intact …

The Drosophila blood–brain barrier regulates sleep via Moody G protein-coupled receptor signaling

S Axelrod, X Li, Y Sun, S Lincoln… - Proceedings of the …, 2023 - National Acad Sciences
Sleep is vital for most animals, yet its mechanism and function remain unclear. We found that
permeability of the BBB (blood–brain barrier)—the organ required for the maintenance of …

Sticky Pi is a high-frequency smart trap that enables the study of insect circadian activity under natural conditions

Q Geissmann, PK Abram, D Wu, CH Haney… - PLoS …, 2022 - journals.plos.org
In the face of severe environmental crises that threaten insect biodiversity, new technologies
are imperative to monitor both the identity and ecology of insect species. Traditionally, insect …

Most sleep does not serve a vital function: Evidence from Drosophila melanogaster

Q Geissmann, EJ Beckwith, GF Gilestro - Science advances, 2019 - science.org
Sleep appears to be a universally conserved phenomenon among the animal kingdom, but
whether this notable evolutionary conservation underlies a basic vital function is still an …

Altered circadian rhythm, sleep, and rhodopsin 7–dependent shade preference during diapause in Drosophila melanogaster

GT Meyerhof, S Easwaran, AE Bontempo… - Proceedings of the …, 2024 - pnas.org
To survive adverse environments, many animals enter a dormant state such as hibernation,
dauer, or diapause. Various Drosophila species undergo adult reproductive diapause in …

Parp mutations protect from mitochondrial toxicity in Alzheimer's disease

Y Yu, G Fedele, I Celardo, SHY Loh, LM Martins - Cell Death & Disease, 2021 - nature.com
Alzheimer's disease is the most common age-related neurodegenerative disorder. Familial
forms of Alzheimer's disease associated with the accumulation of a toxic form of amyloid-β …