Infections with any of the nine human herpes viruses (HHV) can be asymptomatic or life-
threatening. The study of patients with severe diseases caused by HHVs, in the absence of …

Epstein–Barr Virus (EBV) is a gamma-herpes virus that infects 90% of humans without any
symptoms in most cases, but has an oncogenic potential, especially in immunocompromised …

The Nck-associated protein 1–like (NCKAP1L) gene, alternatively called hematopoietic
protein 1 (HEM-1), encodes a hematopoietic lineage–specific regulator of the actin …

Genetic testing has become an integral component of the diagnostic evaluation of patients
with suspected primary immunodeficiency diseases. Results of genetic testing can have a …

An increasing number of primary immunodeficiencies (PIDs) have been identified over the
last decade, which are caused by deleterious mutations in genes encoding for proteins …

Human papillomaviruses (HPVs) are responsible for cutaneous and mucosal lesions.
Persistent HPV infection remains a leading cause of uterine cancer in women, but also of …

Varicella zoster virus (VZV) is a pathogenic human herpes virus which causes varicella as a
primary infection, following which it becomes latent in peripheral autonomic, sensory, and …

Epstein–Barr virus (EBV) is a ubiquitous human pathogen, infecting> 90% of the adult
population. In the vast majority of healthy individuals, infection with EBV runs a relatively …

Human papillomaviruses (HPVs) infect mucosal or cutaneous stratified epithelia. There are
5 genera and more than 200 types of HPV, each with a specific tropism and virulence. HPV …

Motility is a crucial activity of immune cells allowing them to patrol tissues as they
differentiate, sample or exchange information, and execute their effector functions. Although …