HPV: Molecular pathways and targets

S Gupta, P Kumar, BC Das - Current problems in cancer, 2018 - Elsevier
Infection of high-risk human papillomaviruses (HPVs) is a prerequisite for the development
of cervical carcinoma. HPV infections are also implicated in the development of other types …

[HTML][HTML] The challenge of targeting cancer stem cells to halt metastasis

A Agliano, A Calvo, C Box - Seminars in Cancer Biology, 2017 - Elsevier
Despite a continuing debate about the existence of cancer stem cells (CSCs), recent
discoveries have provided further support for their existence and their roles in drug …

Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

A Tyagi, S Sharma, K Wu, SY Wu, F Xing, Y Liu… - Nature …, 2021 - nature.com
Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

Advances in therapeutic targeting of cancer stem cells within the tumor microenvironment: an updated review

K Dzobo, DA Senthebane, C Ganz, NE Thomford… - Cells, 2020 - mdpi.com
Despite great strides being achieved in improving cancer patients' outcomes through better
therapies and combinatorial treatment, several hurdles still remain due to therapy …

Hypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA

G Chen, B Liu, S Yin, S Li, Y Guo, M Wang, K Wang… - Oncogenesis, 2020 - nature.com
Endometrial cancer stem cells (ECSCs) are stem-like cells endowed with self-renewal and
differentiation abilities, and these cells are essential for cancer progression in endometrial …

Pterostilbene suppresses both cancer cells and cancer stem-like cells in cervical cancer with superior bioavailability to resveratrol

HJ Shin, JM Han, YS Choi, HJ Jung - Molecules, 2020 - mdpi.com
Increasing studies have reported that cancer stem cells (CSCs) play critical roles in
therapeutic resistance, recurrence, and metastasis of tumors, including cervical cancer …

Targeting therapy-resistant cancer stem cells by hyperthermia

AL Oei, LEM Vriend, PM Krawczyk… - International Journal …, 2017 - Taylor & Francis
Eradication of all malignant cells is the ultimate but challenging goal of anti-cancer
treatment; most traditional clinically-available approaches fail because there are cells in a …

Physical interaction between STAT3 and AP1 in cervical carcinogenesis: implications in HPV transcription control

K Thakur, D Janjua, N Aggarwal, A Chhokar… - … et Biophysica Acta (BBA …, 2023 - Elsevier
The constitutive activation and aberrant expression of Signal Transducer and Activator of
Transcription 3 (STAT3) plays a key role in initiation and progression of cervical cancer …

Cervical cancer stem cells and other leading factors associated with cervical cancer development

G Mendoza-Almanza, E Ortiz-Sanchez… - Oncology …, 2019 - spandidos-publications.com
Cervical cancer (CC) is one of the leading causes of cancer-associated mortalities in women
from developing countries. Similar to other types of cancer, CC is considered to be a …

Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle …

L Wang, Y Liu, Y Zhou, J Wang, L Tu, Z Sun… - Journal of Experimental …, 2019 - Springer
Background Zoledronic acid is the most potent osteoclast inhibitor and is widely used for
advanced cancer patients with bone metastasis, but its role on cancer stem cells (CSCs) …