Neuroblastomas are tumours of sympathetic origin, with a heterogeneous clinical course
ranging from localized or spontaneously regressing to widely metastatic disease …

Female patients with childhood, adolescent, and young adult cancer are at increased risk for
fertility impairment when treatment adversely affects the function of reproductive organs …

Introduction: Children with neuroblastoma have widely divergent outcomes, ranging from
cure in> 90% of patients with low risk disease to< 50% for those with high risk disease …

Neuroblastoma (NB), the most common extracranial tumor of childhood, is a cancer of
primordial neural crest cells that give rise to sympathetic neural ganglia and adrenal …

Patients with high risk neuroblastoma have a poor prognosis and survivors are often left with
debilitating long term sequelae from treatment. Even after integration of anti-GD2 …

Purpose Anti-GD2 monoclonal antibody (MoAb) combined with granulocyte-macrophage
colony-stimulating factor (GM-CSF) has shown efficacy against neuroblastoma (NB) …

Simple Summary Neuroblastoma is one of the most diffuse and the deadliest cancer in
children. While many advances have been made in the last few decades to improve patients' …

Background Anti-cancer treatment may reduce the fertile life span and induce premature
menopause. This review aims to provide an overview of the available literature on effects of …

BACKGROUND Survivors of childhood cancer are at risk of nonsurgical premature
menopause (NSPM). To the authors' knowledge, risk factors for NSPM and its impact on …

Background: Childhood neuroblastoma describes a heterogeneous group of extracranial
solid tumors, that are treated per risk profile. We sought to describe treatment patterns and …