DNA quadruple helices in nanotechnology

JL Mergny, D Sen - Chemical Reviews, 2019 - ACS Publications
DNA has played an early and powerful role in the development of bottom-up
nanotechnologies, not least because of DNA's precise, predictable, and controllable …

Logic gates based on G-quadruplexes: principles and sensor applications

Y Guo, W Yao, Y Xie, X Zhou, J Hu, R Pei - Microchimica Acta, 2016 - Springer
Abstract This review (with 139 refs.) gives a fundamental introduction into the sensors and
logic gates based on G-quadruplexes (G4s). G4 characterizes vibrant binding activities and …

Interaction of an iridium (III) complex with G-quadruplex DNA and its application in luminescent switch-on detection of siglec-5

S Lin, L Lu, TS Kang, JL Mergny, CH Leung… - Analytical …, 2016 - ACS Publications
Sialic acid (Sia) binding immunoglobulin (Ig)-like lectin-5 (Siglec-5) is a type-I
transmembrane protein, and it has been demonstrated as a biomarker of granulocytic …

Multiple types of logic gates based on a single G-quadruplex DNA strand

Y Guo, L Zhou, L Xu, X Zhou, J Hu, R Pei - Scientific Reports, 2014 - nature.com
In this work, we demonstrate the use of a single DNA strand and G-quadruplex-specific dye
NMM as a label-free switch for the construction of series of basic logic gates (YES, NOT, OR …

Label-free detection of Pb 2+ based on aggregation-induced emission enhancement of Au-nanoclusters

L Ji, Y Guo, S Hong, Z Wang, K Wang, X Chen… - RSC Advances, 2015 - pubs.rsc.org
Interestingly, the glutathione capped Au-nanoclusters presented here showed a unique
optical performance compared with their homological AuNPs with larger size. The …

Label-free detection of T4 DNA ligase and polynucleotide kinase activity based on toehold-mediated strand displacement and split G-quadruplex probes

Y Guo, Q Wang, Z Wang, X Chen, L Xu, J Hu… - Sensors and Actuators B …, 2015 - Elsevier
Herein, an efficient pair of split G-quadruplex probes was selected (S/N= 21) to construct a
simple, rapid and label-free technique for the detections of T4 DNA ligase and PNK activity …

Selection and characterization of malachite green aptamers for the development of light–up probes

H Wang, J Wang, N Sun, H Cheng, H Chen… - …, 2016 - Wiley Online Library
The light‐up fluorogenic dyes exhibit excellent behavior that autofluorescence is very low
but substantially increases when interacting with their ligands. Aptamers are single …

A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity

S Lin, TS Kang, L Lu, W Wang, DL Ma… - Biosensors and …, 2016 - Elsevier
Thymine DNA glycosylase (TDG) performs essential functions in maintaining genetic
integrity and epigenetic regulation, which also plays an essential role in DNA demethylation …

Label-free DNA-based biosensors using structure-selective light-up dyes

Y Guo, L Xu, S Hong, Q Sun, W Yao, R Pei - Analyst, 2016 - pubs.rsc.org
Label-free biosensors (LFBs) have demonstrated a great potential in cost-effective
applications, and most of the DNA-based LFBs are based on the principle of binding …

Label-free ratiometric DNA detection using two kinds of interaction-responsive emission dyes

Y Guo, Q Chen, Y Qi, Y Xie, H Qian, W Yao… - Biosensors and …, 2017 - Elsevier
A novel ratiometric method with label-free and dual-wavelength signal outputs was
developed for DNA detection by employing two kinds of structure-specific dyes that …