With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

In recent years, lipid metabolism has garnered significant attention as it provides the
necessary building blocks required to sustain tumor growth and serves as an alternative fuel …

Peroxisome proliferator-activated receptor-delta (PPAR-δ), one of three members of the
PPAR group in the nuclear receptor superfamily, is a ligand-activated transcription factor …

Disordered proteins have long been known to help mediate tolerance to different abiotic
stresses including freezing, osmotic stress, high temperatures, and desiccation in a diverse …

Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …

The increasing prevalence of obesity worldwide is associated with an increased risk of
various diseases, including multiple metabolic diseases, cardiovascular diseases, and …

Highlights•Fatty acid binding protein 5 (FABP5) is upregulated in many cancers, particularly
prostate cancer (PC).•FABP5 facilitates the delivery of fatty acids to peroxisome proliferator …

Chemical contaminants can cause adverse effects by binding to the liver-fatty acid binding
protein (L-FABP) and peroxisome proliferator-activated nuclear receptor γ (PPARγ), which …

Despite the remarkable clinical success of immunotherapy and molecular targeted therapy
in patients with advanced tumors, chemotherapy remains the most commonly used …

Cisplatin is one of the most potent and widely used chemotherapeutic agent in the treatment
of several solid tumors, despite the high toxicity and the frequent relapse of patients due to …