Phytocompound mediated blockage of quorum sensing cascade in ESKAPE pathogens

S Ghosh, D Lahiri, M Nag, A Dey, S Pandit, T Sarkar… - Antibiotics, 2022 - mdpi.com
Increased resistance of Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Antimicrobial, Antioxidant, Anti-Acetylcholinesterase, Antidiabetic, and Pharmacokinetic Properties of Carum carvi L. and Coriandrum sativum L. Essential Oils Alone …

H Hajlaoui, S Arraouadi, E Noumi, K Aouadi, M Adnan… - Molecules, 2021 - mdpi.com
Herbs and spices have been used since antiquity for their nutritional and health properties,
as well as in traditional remedies for the prevention and treatment of many diseases …

Tomatidine and patchouli alcohol as inhibitors of SARS-CoV-2 enzymes (3CLpro, PLpro and NSP15) by molecular docking and molecular dynamics simulations

R Zrieq, I Ahmad, M Snoussi, E Noumi, M Iriti… - International Journal of …, 2021 - mdpi.com
Considering the current dramatic and fatal situation due to the high spreading of SARS-CoV-
2 infection, there is an urgent unmet medical need to identify novel and effective approaches …

Design, synthesis, in vitro anticancer and antimicrobial evaluation, SAR analysis, molecular docking and dynamic simulation of new pyrazoles, triazoles and …

HA Radwan, I Ahmad, IMM Othman… - Journal of Molecular …, 2022 - Elsevier
A new series of pyrazoles, triazoles and pyridazines based isoxazole were synthesized, and
well characterized. Their antibacterial, antifungal and cytotoxic activities were successfully …

A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

LM Aroua, HR Almuhaylan, FM Alminderej… - Bioorganic …, 2021 - Elsevier
Synthetic routes to a series of benzoylarylbenzimidazol 3a-h have been derived from 3, 4-
diaminobenzophenone and an appropriate arylaldehyde in the presence of ammonium …

Antioxidant Activities of a New Chemotype of Piper cubeba L. Fruit Essential Oil (Methyleugenol/Eugenol): In Silico Molecular Docking and ADMET Studies

F Alminderej, S Bakari, TI Almundarij, M Snoussi… - Plants, 2020 - mdpi.com
Piper cubeba L. fruit is an important species used in folk medicine for different types of pains
such as rheumatism, chills, flu, colds, muscular aches, and fever. This study examines the …

Toward a treatment of antibacterial and antifungal infections: Design, synthesis and in vitro activity of novel arylhydrazothiazolylsulfonamides analogues and their …

IMM Othman, MH Mahross, MAM Gad-Elkareem… - Journal of Molecular …, 2021 - Elsevier
To find out effective new antibacterial agents, a series of novel aryl-hydrazothiazolyl-
sulfonamide derivatives 3a-e were synthesized and well characterized by analytical and …

GC/MS Profiling, Antibacterial, Anti-Quorum Sensing, and Antibiofilm Properties of Anethum graveolens L. Essential Oil: Molecular Docking Study and In-Silico ADME …

E Noumi, I Ahmad, M Adnan, A Merghni, H Patel… - Plants, 2023 - mdpi.com
Anethum graveolens L. has been known as an aromatic, medicinal, and culinary herb since
ancient times. The main purpose of this study was to determine the chemical composition …

New Biological and Chemical Evidences of Two Lamiaceae Species (Thymbra capitata and Thymus sipyleus subsp. rosulans): In Vitro, In Silico and Ex Vivo …

EJ Llorent-Martínez, A Ruiz-Medina, G Zengin, G Ak… - Molecules, 2022 - mdpi.com
In this study, the methanolic and infusion extracts of two species, Thymbra capitata and
Thymus sipyleus subsp. rosulans, were tested for their chemical composition and biological …

[HTML][HTML] Design, synthesis, biological evaluation and in silico studies of novel 1, 2, 3-triazole linked benzoxazine-2, 4-dione conjugates as potent antimicrobial …

MB Hammouda, I Ahmad, A Hamdi, A Dbeibia… - Arabian Journal of …, 2022 - Elsevier
In an attempt to rationalize the search for new potential anti-inflammatory and anti-infection
agents, a new series of 1, 4-and 1, 5-disubstituted 1, 2, 3-triazoles linked benzoxazine …