MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

Background and Aims Animal models of human disease are a key component of
translational hepatology research, yet there is no consensus on which model is optimal for …

Since their discovery in the 1980s and 1990s, the human protein lysine acetyltransferase
encoded by the paralogous p300 and CBP genes has received much interest. p300/CBP …

Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …

MicroRNAs (miRNAs) regulate a wide variety of biological processes and contribute to
metabolic homeostasis. Here, we demonstrate that microRNA-223 (miR-223), an miRNA …

Breast cancer is a major health problem that affects one in eight women worldwide. As such,
detecting breast cancer at an early stage anticipates better disease outcome and prolonged …

The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …

In hepatocellular carcinoma (HCC), dysregulated expression of microRNA‐224 (miR‐224)
and impaired autophagy have been reported separately. However, the relationship between …

MicroRNAs (miRNAs) play pivotal roles in numerous biological processes, and their
dysregulation is a common feature of human cancer. Thanks to recent advances in the …

microRNAs (miRNAs) are small, non-coding RNAs with critical roles in fine-tuning a wide
array of biological processes including development, metabolism, and homeostasis …