Emerging deep eutectic solvents for food waste valorization to achieve sustainable development goals: Bioactive extractions and food applications

S Mavai, A Bains, K Sridhar, P Chawla, M Sharma - Food Chemistry, 2024 - Elsevier
Food waste, accounting for about one-third of the total global food resources wasted each
year, is a substantial challenge to global sustainability, contributing to adverse …

[HTML][HTML] Bioactive compounds from nature: Antioxidants targeting cellular transformation in response to epigenetic perturbations induced by oxidative stress

A Bouyahya, S Bakrim, S Aboulaghras… - Biomedicine & …, 2024 - Elsevier
Oxidative stress results from a persistent imbalance in oxidation levels that promotes
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …

[HTML][HTML] The Antinociceptive Role of Nrf2 in Neuropathic Pain: From Mechanisms to Clinical Perspectives

K Petrikonis, J Bernatoniene, DM Kopustinskiene… - Pharmaceutics, 2024 - mdpi.com
Neuropathic pain, a chronic condition resulting from nerve injury or dysfunction, presents
significant therapeutic challenges and is closely associated with oxidative stress and …

Nrf2 pathways in neuroprotection: Alleviating mitochondrial dysfunction and cognitive impairment in aging

AA Bhat, E Moglad, A Goyal, M Afzal, R Thapa… - Life Sciences, 2024 - Elsevier
Mitochondrial dysfunction and cognitive impairment are widespread phenomena among the
elderly, being crucial factors that contribute to neurodegenerative diseases. Nuclear factor …

[HTML][HTML] Suppression the glucose-induced ferroptosis in endothelial cells by 4OI-loading exosomes hydrogel for the treatment of diabetic foot ulcer

K Shen, R Zheng, B Yu, H Zhang, P Wang… - Chemical Engineering …, 2024 - Elsevier
The prevalence of diabetic foot ulcer in individuals with diabetes is approximately 15%, and
it is frequently accompanied by vascular dysfunction and infection. The management …

NRF2-mediated regulation of lipid pathways in viral infection

K Muzammil, ZS Ghnim, IS Gataa… - Molecular Aspects of …, 2024 - Elsevier
The first line of defense against viral infection of the host cell is the cellular lipid membrane,
which is also a crucial first site of contact for viruses. Lipids may sometimes be used as viral …

Therapeutic potential of plasma-treated solutions in atopic dermatitis

T Yin, S Feng, H Zhu, R Bai, X Gan, K He, W Du… - Free Radical Biology …, 2024 - Elsevier
Atopic Dermatitis (AD) is a prevalent inflammatory skin disease that is currently incurable.
Plasma-treated solutions (PTS)(eg, culture media, water, or normal saline, previously …

DNMT inhibitor, 5-aza-2′-deoxycytidine mitigates di (2-ethylhexyl) phthalate-induced aggravation of psoriasiform inflammation in mice via reduction in global DNA …

AS Alfardan, A Nadeem, SF Ahmad, NO Al-Harbi… - International …, 2024 - Elsevier
Psoriasis is classified as an autoimmune disorder characterized by abnormal immune
response leading to the development of chronic dermal inflammation. Most individuals have …

Mechanism of vitamin C alleviating the immunotoxicity of 17α-methyltestosterone in Carassius auratus

T Li, Z Xiong, Y Liu, H Zhao, W Rong, Y Chen, G Chen… - BMC genomics, 2024 - Springer
Background In recent years, the use of endocrine-disrupting chemicals (EDCs) has become
increasingly common, leading to severe environmental pollution and harm to aquatic …

ROS-responsive caffeic acid phenethyl ester-conjugated carboxymethyl chitosan hydrogel for treatment of periodontitis

G Wang, Y Wang, S Li, Z Shu, M Tang, X Ma… - Journal of Drug Delivery …, 2024 - Elsevier
Periodontitis, an inflammatory disease caused by bacterial infection, is characterized by an
abundance of reactive oxygen species (ROS) in the affected area. These ROS induce …