Protein kinase C at the crossroad of mutations, cancer, targeted therapy and immune response

A Aquino, N Bianchi, A Terrazzan, O Franzese - Biology, 2023 - mdpi.com
Simple Summary This review aims to analyze the clinical drawbacks faced by PKC inhibitors
and uncovering aspects that might potentially interfere with the clinical outcome of …

Myeloid cells in the era of cancer Immunotherapy: top 3 unanswered questions

M Chaib, UA Tanveer, L Makowski - Pharmacology & therapeutics, 2023 - Elsevier
Myeloid cells are increasingly being recognized as central players orchestrating or
suppressing antitumor immune responses. With the advent of high-resolution analytical …

FXR agonism with bile acid mimetic reduces pre-clinical triple-negative breast cancer burden

SC Joseph, S Eugin Simon, MS Bohm, M Kim, ME Pye… - Cancers, 2024 - mdpi.com
Simple Summary Breast cancer (BC) is the most common malignancy and the leading cause
of cancer mortality in women. It is possible that signals arising from the gut microbiome are …