[HTML][HTML] Disulfiram encapsulated in polymer nanoparticles ameliorates thioacetamide-induced liver injury

W Xu, Y Kadoya, K Sennari, W Islam, T Zhang… - Journal of Drug Delivery …, 2023 - Elsevier
Liver disease is the cause of approximately 2 million deaths per year worldwide. Liver
macrophages (Kupffer cells), the most abundant immune cells in the liver, play important …

MitoTracker Red for isolation of zone-specific hepatocytes and characterization of hepatic sublobular metabolism

M Savoca, K Takemoto, J Hu, L Li, BJ Kendrick… - Biochemical and …, 2024 - Elsevier
Background The liver lobule is divided into three zones or regions: periportal (PP or Zone 1)
that is highly oxidative and active in ureagenesis, pericentral (PC or Zone 3) that is more …

Evaluation and analysis of novel germline variants in ethanol metabolism pathway genes predisposition to liver disease

PP Das, MJ Kalita, AJ Talukdar, FM Khan, K Dutta… - Gene, 2023 - Elsevier
The pathogenetic events of liver disease are seemingly determined by factors linked to
ethanol metabolism. The variations in genes encoding enzymes of the ethanol metabolic …