Many human cancers are associated with characteristic chromosomal rearrangements,
especially hematopoietic cancers such as leukemias and lymphomas. The first and most …

This study explores the roles of genome copy number abnormalities (CNAs) in breast cancer
pathophysiology by identifying associations between recurrent CNAs, gene expression, and …

The basal molecular subtype of breast cancer (BC) is defined by the mRNA expression
pattern of an intrinsic∼ 500‐gene set. It is the most homogeneous subtype in transcriptional …

In human carcinomas, especially breast cancer, chromosome arm 8p is frequently involved
in complex chromosomal rearrangements that combine amplification at 8p11-12, break in …

Genomic gain represents an important mechanism in the activation of proto‐oncogenes. In
many instances, induced oncogenes hold clinical implications both as prognostic markers …

Genetic and epigenetic alterations have been identified that lead to transcriptional
deregulation in cancers. Genetic mechanisms may affect single genes or regions containing …

A high percentage of uveal melanoma patients develop metastatic tumors predominantly in
the liver. We studied the molecular profiles derived from gene expression microarrays and …

The scaffolding adapter GAB2 maps to a region (11q13-14) commonly amplified in human
breast cancer, and is overexpressed in breast cancer cell lines and primary tumors, but its …

Background Current diagnosis and treatment of urinary bladder cancer (BC) has shown
great progress with the utilization of microarrays. Purpose Our goal was to identify common …

Along the transformation process, cells accumulate DNA aberrations, including mutations,
translocations, amplifications, and deletions. Despite numerous studies, the overall effects of …