[HTML][HTML] Blood flow mechanics in cardiovascular development

F Boselli, JB Freund, J Vermot - Cellular and Molecular Life Sciences, 2015 - Springer
Hemodynamic forces are fundamental to development. Indeed, much of cardiovascular
morphogenesis reflects a two-way interaction between mechanical forces and the gene …

Topology and hemodynamics of the cortical cerebrovascular system

S Hirsch, J Reichold, M Schneider… - Journal of Cerebral …, 2012 - journals.sagepub.com
The cerebrovascular system continuously delivers oxygen and energy substrates to the
brain, which is one of the organs with the highest basal energy requirement in mammals …

Methods of blood flow modelling

N Bessonov, A Sequeira, S Simakov… - … modelling of natural …, 2016 - mmnp-journal.org
This review is devoted to recent developments in blood flow modelling. It begins with the
discussion of blood rheology and its non-Newtonian properties. After that we will present …

[HTML][HTML] Multiscale modelling of blood flow in cerebral microcirculation: Details at capillary scale control accuracy at the level of the cortex

M Peyrounette, Y Davit, M Quintard, S Lorthois - PloS one, 2018 - journals.plos.org
Aging or cerebral diseases may induce architectural modifications in human brain
microvascular networks, such as capillary rarefaction. Such modifications limit blood and …

Spheres in the vicinity of a bifurcation: elucidating the Zweifach–Fung effect

V Doyeux, T Podgorski, S Peponas, M Ismail… - Journal of Fluid …, 2011 - cambridge.org
The problem of the splitting of a suspension in bifurcating channels divided into two
branches of non-equal flow rates is addressed. As has long been observed, in particular in …

Hemodynamic regulation allows stable growth of microvascular networks

Y Qi, SS Chang, Y Wang, C Chen… - Proceedings of the …, 2024 - National Acad Sciences
How do vessels find optimal radii? Capillaries are known to adapt their radii to maintain the
shear stress of blood flow at the vessel wall at a set point, yet models of adaptation purely …

A few upstream bifurcations drive the spatial distribution of red blood cells in model microfluidic networks

A Merlo, M Berg, P Duru, F Risso, Y Davit, S Lorthois - Soft Matter, 2022 - pubs.rsc.org
The physics of blood flow in small vessel networks is dominated by the interactions between
Red Blood Cells (RBCs), plasma and blood vessel walls. The resulting couplings between …

[HTML][HTML] Red blood cells stabilize flow in brain microvascular networks

F Schmid, MJP Barrett, D Obrist, B Weber… - PLoS computational …, 2019 - journals.plos.org
Capillaries are the prime location for oxygen and nutrient exchange in all tissues. Despite
their fundamental role, our knowledge of perfusion and flow regulation in cortical capillary …

A mesoscale computational model for microvascular oxygen transfer

L Possenti, A Cicchetti, R Rosati, D Cerroni… - Annals of Biomedical …, 2021 - Springer
We address a mathematical model for oxygen transfer in the microcirculation. The model
includes blood flow and hematocrit transport coupled with the interstitial flow, oxygen …

[HTML][HTML] In vitro investigations of red blood cell phase separation in a complex microchannel network

A Mantegazza, F Clavica, D Obrist - Biomicrofluidics, 2020 - pubs.aip.org
Microvascular networks feature a complex topology with multiple bifurcating vessels.
Nonuniform partitioning (phase separation) of red blood cells (RBCs) occurs at diverging …