Single-cell analysis of acute lymphoblastic and lineage-ambiguous leukemia: approaches and molecular insights
I Iacobucci, MT Witkowski, CG Mullighan - Blood, 2023 - ashpublications.org
Despite recent progress in identifying the genetic drivers of acute lymphoblastic leukemia
(ALL), prognosis remains poor for those individuals who experience disease recurrence …
(ALL), prognosis remains poor for those individuals who experience disease recurrence …
Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia
Sequencing of bulk tumor populations has improved genetic classification and risk
assessment of B-ALL, but does not directly examine intratumor heterogeneity or infer …
assessment of B-ALL, but does not directly examine intratumor heterogeneity or infer …
Single-cell sequencing: biological insight and potential clinical implications in pediatric leukemia
Simple Summary Leukemia is the most common type of childhood malignancy. While the
clinical management of pediatric acute leukemia, especially acute lymphoblastic leukemia …
clinical management of pediatric acute leukemia, especially acute lymphoblastic leukemia …
Establishment and verification of a TME prognosis scoring model based on the acute myeloid leukemia single-cell transcriptome
P Miao, J Yu, Z Chen, S Qian, C Chen - Scientific Reports, 2024 - nature.com
The tumor microenvironment (TME) plays an important role in the occurrence and
progression of Acute Myeloid Leukemia (AML). Single-cell sequencing has enabled …
progression of Acute Myeloid Leukemia (AML). Single-cell sequencing has enabled …
Bone marrow stromal cell regeneration profile in treated B-cell precursor acute lymphoblastic leukemia patients: association with MRD status and patient outcome
Simple Summary For the last 20 years, measurable residual disease (MRD) has proven to
be a strong prognostic factor in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) …
be a strong prognostic factor in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) …
[PDF][PDF] Bone Marrow Stromal Cell Regeneration Profile in Treated B-Cell Precursor Acute Lymphoblastic Leukemia Patients: Association with MRD Status and Patient …
PHO Unit - 2022 - scholarlypublications …
For the last two decades, measurable residual disease (MRD) has become one of the most
powerful independent prognostic factors in B-cell precursor acute lymphoblastic leukemia …
powerful independent prognostic factors in B-cell precursor acute lymphoblastic leukemia …
[PDF][PDF] Single-Cell Sequencing: Biological Insight and Potential Clinical Implications in Pediatric Leukemia. Cancers 2021, 13, 5658
Single-cell sequencing (SCS) provides high-resolution insight into the genomic,
epigenomic, and transcriptomic landscape of oncohematological malignancies including …
epigenomic, and transcriptomic landscape of oncohematological malignancies including …