Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity
Doxorubicin (DOX) is an anthracycline antibiotic, which is effectively used in the treatment of
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …
Recent advances in protection against doxorubicin-induced toxicity
R Injac, B Strukelj - Technology in cancer research & …, 2008 - journals.sagepub.com
Anthracycline antibiotics are among the most effective and commonly used anticancer
drugs. Unfortunately, their clinical use is restricted by dose-dependent toxicity. Doxorubicin …
drugs. Unfortunately, their clinical use is restricted by dose-dependent toxicity. Doxorubicin …
Protective effects of fullerenol C60 (OH) 24 against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats with colorectal cancer
R Injac, M Perse, M Cerne, N Potocnik, N Radic… - Biomaterials, 2009 - Elsevier
The effects of fullerenol C60 (OH) 24 (Frl) at doses of 25, 50, and 100mg/kg/week (for a time-
span of 3 weeks) on heart and liver tissue after doxorubicin (Dox)-induced toxicity in rats …
span of 3 weeks) on heart and liver tissue after doxorubicin (Dox)-induced toxicity in rats …
Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells
M Xu, Y Xiong, J Liu, J Qian, L Zhu, J Gao - Acta Pharmacologica Sinica, 2012 - nature.com
Aim: To investigate whether asiatic acid (AA), a pentacyclic triterpene in Centella asiatica,
exerted neuroprotective effects in vitro and in vivo, and to determine the underlying …
exerted neuroprotective effects in vitro and in vivo, and to determine the underlying …
[PDF][PDF] An ethnobotanical survey of Rajshahi district in Rajshahi division, Bangladesh
A Nawaz, M Hossain, M Karim, M Khan… - … Eurasian Journal of …, 2009 - academia.edu
Rajshahi district falls within the Rajshahi division of Bangladesh. It is bordered by Naogaon
district on the north, Kushtia district on the south, Natore district on the east and Nawabganj …
district on the north, Kushtia district on the south, Natore district on the east and Nawabganj …
Enrichment and purification of madecassoside and asiaticoside from Centella asiatica extracts with macroporous resins
G Jia, X Lu - Journal of Chromatography A, 2008 - Elsevier
In present study, the performance and separation characteristics of five macroporous resins
for the enrichment and purification of asiaticoside and madecassoside from Centella asiatica …
for the enrichment and purification of asiaticoside and madecassoside from Centella asiatica …
Time to change: a systems pharmacology approach to disentangle mechanisms of drug-induced mitochondrial toxicity
CA Hoogstraten, JJ Lyon, JAM Smeitink… - Pharmacological …, 2023 - Elsevier
An increasing number of commonly prescribed drugs are known to interfere with
mitochondrial function, which is associated with almost half of all Food and Drug …
mitochondrial function, which is associated with almost half of all Food and Drug …
Assessing drug-induced mitochondrial toxicity in cardiomyocytes: implications for preclinical cardiac safety evaluation
X Tang, Z Wang, S Hu, B Zhou - Pharmaceutics, 2022 - mdpi.com
Drug-induced cardiotoxicity not only leads to the attrition of drugs during development, but
also contributes to the high morbidity and mortality rates of cardiovascular diseases …
also contributes to the high morbidity and mortality rates of cardiovascular diseases …
Ethnobotany, Phytochemistry and Pharmacological Features of Centella asiatica: A Comprehensive Review
FA Torbati, M Ramezani, R Dehghan, MS Amiri… - … Properties of Plant …, 2021 - Springer
Centella asiatica (CA) or Gotu cola is an herbal plant from the Apiaceae family with a long
history of usage in different traditional medicines. It has long been used for the treatment of …
history of usage in different traditional medicines. It has long been used for the treatment of …
Potential biomarkers in mouse myocardium of doxorubicin-induced cardiomyopathy: a metabonomic method and its application
G Tan, Z Lou, W Liao, Z Zhu, X Dong, W Zhang, W Li… - PloS one, 2011 - journals.plos.org
Background Doxorubicin (DOX) is one of the most potent antitumor agents available;
however, its clinical use is limited because of the risk of severe cardiotoxicity. Though …
however, its clinical use is limited because of the risk of severe cardiotoxicity. Though …