Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy

H Niu, J Liu, HM O'Connor, T Gunnlaugsson… - Chemical Society …, 2023 - pubs.rsc.org
Typical PeT-based fluorescent probes are multi-component systems where a fluorophore is
connected to a recognition/activating group by an unconjugated linker. PeT-based …

RONS and oxidative stress: An overview of basic concepts

AK Aranda-Rivera, A Cruz-Gregorio… - Oxygen, 2022 - mdpi.com
Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …

Emerging roles of energy metabolism in ferroptosis regulation of tumor cells

X Yao, W Li, D Fang, C Xiao, X Wu, M Li… - Advanced …, 2021 - Wiley Online Library
Ferroptosis is a new form of regulated cell death, which is characterized by the iron‐
dependent accumulation of lethal lipid peroxides and involved in many critical diseases …

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

AC Sedgwick, L Wu, HH Han, SD Bull, XP He… - Chemical Society …, 2018 - pubs.rsc.org
In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …

Ferroptosis is a type of autophagy-dependent cell death

B Zhou, J Liu, R Kang, DJ Klionsky, G Kroemer… - Seminars in cancer …, 2020 - Elsevier
Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …

Glutathione-related enzymes and proteins: a review

J Vašková, L Kočan, L Vaško, P Perjési - Molecules, 2023 - mdpi.com
The tripeptide glutathione is found in all eukaryotic cells, and due to the
compartmentalization of biochemical processes, its synthesis takes place exclusively in the …

Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

W Abdullahi, D Tripathi… - American Journal of …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) is a physical and biochemical barrier that precisely controls
cerebral homeostasis. It also plays a central role in the regulation of blood-to-brain flux of …

[HTML][HTML] Oxidative stress in bone remodeling: role of antioxidants

V Domazetovic, G Marcucci, T Iantomasi… - Clinical Cases in …, 2017 - ncbi.nlm.nih.gov
ROS are highly reactive molecules which consist of a number of diverse chemical species,
including radical and non-radical oxygen species. Oxidative stress occurs as a result of an …

The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression

Y Wu, S Zhang, X Gong, S Tam, D Xiao, S Liu, Y Tao - Molecular cancer, 2020 - Springer
Ferroptosis, a novel form of regulated cell death, is different from other types of cell death in
morphology, genetics and biochemistry. Increasing evidence indicates that ferroptosis has …

Serine and one-carbon metabolism in cancer

M Yang, KH Vousden - Nature Reviews Cancer, 2016 - nature.com
The non-essential amino acid serine supports several metabolic processes that are crucial
for the growth and survival of proliferating cells, including protein, amino acid and …