Japanese encephalitis virus: the emergence of genotype IV in Australia and its potential endemicity

JS Mackenzie, DT Williams, AF van den Hurk… - Viruses, 2022 - mdpi.com
A fatal case of Japanese encephalitis (JE) occurred in northern Australia in early 2021.
Sequence studies showed that the virus belonged to genotype IV (GIV), a genotype …

The reemerging and outbreak of genotypes 4 and 5 of Japanese encephalitis virus

W Zhang, Q Yin, H Wang, G Liang - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The Japanese encephalitis virus (JEV) is classified into five distinct genotypes, with
genotypes 1 and 3 historically showing higher activity. These genotypes are the primary …

A chimeric vaccine derived from Australian genotype IV Japanese encephalitis virus protects mice from lethal challenge

JJ Harrison, W Nguyen, MS Morgan, B Tang… - npj Vaccines, 2024 - nature.com
In 2022, a genotype IV (GIV) strain of Japanese encephalitis virus (JEV) caused an
unprecedented and widespread outbreak of disease in pigs and humans in Australia. As no …

Shift in dominant genotypes of Japanese encephalitis virus and its impact on current vaccination strategies

Q Xia, Y Yang, Y Zhang, L Zhou, X Ma, C Xiao… - Frontiers in …, 2023 - frontiersin.org
Japanese encephalitis (JE) is a zoonotic ailment from the Japanese encephalitis virus (JEV).
JEV belongs to the flavivirus genus and is categorized into a solitary serotype consisting of …

Re-emerged genotype IV of Japanese encephalitis virus is the youngest virus in evolution

G Xu, T Gao, Z Wang, J Zhang, B Cui, X Shen, A Zhou… - Viruses, 2023 - mdpi.com
An outbreak of viral encephalitis caused by a Japanese encephalitis virus (JEV) genotype IV
infection occurred in Australia between 2021 and 2022. A total of 47 cases and seven …

Growth, pathogenesis, and serological characteristics of the Japanese encephalitis virus genotype IV recent strain 19CxBa-83-Cv

S Tajima, T Maeki, E Nakayama, AN Faizah… - Viruses, 2023 - mdpi.com
Genotype IV Japanese encephalitis (JE) virus (GIV JEV) is the least common and most
neglected genotype in JEV. We evaluated the growth and pathogenic potential of the GIV …

Australian Culex annulirostris mosquitoes are competent vectors for Japanese encephalitis virus genotype IV

MJ Klein, SA Jackson, WW Suen, J Payne… - Emerging Microbes & …, 2024 - Taylor & Francis
Japanese encephalitis virus (JEV) is transmitted by Culex species of mosquitoes. In 2022,
JEV belonging to a previously unrecognized lineage of genotype IV (GIV) caused a major …

Japanese encephalitis virus: epidemiology and risk-based surveillance approaches for New Zealand

RS Morris, PC Bingham - New Zealand Veterinary Journal, 2023 - Taylor & Francis
The introduction and subsequent rapid spread of Japanese encephalitis virus genotype IV
across all Australian mainland states and the Northern Territory since late 2021 has …

Japanese encephalitis virus: an emerging and re-emerging virus in Australia

JS Mackenzie, DT Williams - Microbiology Australia, 2022 - CSIRO Publishing
Japanese encephalitis virus (JEV) first emerged in the Torres Strait of north-eastern
Australia in 1995, with three human cases, and widespread infection of pigs on a number of …

RAPIDprep: A Simple, Fast Protocol for RNA Metagenomic Sequencing of Clinical Samples

RL Tulloch, K Kim, C Sikazwe, A Michie, R Burrell… - Viruses, 2023 - mdpi.com
Emerging infectious disease threats require rapid response tools to inform diagnostics,
treatment, and outbreak control. RNA-based metagenomics offers this; however, most …