Volumetric reductions in the hippocampus and medial prefrontal cortex (mPFC) are among
the most well-documented neural abnormalities in major depressive disorder (MDD) …

Depression is the leading cause of disability around the world, but little is known about its
pathology. Currently, the diagnosis of depression is made based on clinical manifestations …

Finding robust brain substrates of mood disorders is an important target for research. The
degree to which major depression (MDD) and bipolar disorder (BD) are associated with …

The high comorbidity of Major Depressive Disorder (MDD), Anxiety Disorders (ANX), and
Posttraumatic Stress Disorder (PTSD) has hindered the study of their structural neural …

Abstract Treatment-resistant depression (TRD) is a debilitating condition associated with
higher medical costs, increased illness burden, and reduced quality of life compared to non …

Major depressive disorder (MDD) is a leading cause of disability worldwide. After the first
episode, patients with remitted MDD have a 60% chance of experiencing a second episode …

Obesity is one of the most prevalent somatic comorbidities of major depressive disorder
(MDD). Both disorders rank among the leading challenges in public health and have been …

Importance The behavioral and cognitive symptoms of severe psychotic disorders overlap
with those seen in dementia. However, shared brain alterations remain disputed, and their …

Though numerous studies have implicated structural abnormalities in chronically depressive
patients, relatively little attention has been paid to the brain alterations in patients …

Abstract Yueju, a Traditional Chinese Medicine formula, exhibited fast-onset antidepressant
responses similar to ketamine. This study focused on assessing the rapid and persistent …