[HTML][HTML] A more holistic perspective of Alzheimer's disease: roles of gut microbiome, adipocytes, HPA axis, melatonergic pathway and astrocyte mitochondria in the …
G Anderson - Frontiers in Bioscience-Landmark, 2023 - imrpress.com
Alzheimer's disease is widely regarded as poorly treated due to poor conceptualization. For
40 years, Alzheimer's disease pathophysiology has focused on two culprits, amyloid-β …
40 years, Alzheimer's disease pathophysiology has focused on two culprits, amyloid-β …
Recent Developments in Glioblastoma‐On‐A‐Chip for Advanced Drug Screening Applications
Glioblastoma (GBM) is an aggressive form of cancer, comprising≈ 80% of malignant brain
tumors. However, there are no effective treatments for GBM due to its heterogeneity and the …
tumors. However, there are no effective treatments for GBM due to its heterogeneity and the …
Recent update on PET/CT Radiotracers for Imaging Cerebral Glioma
D Kim, SH Lee, HS Hwang, SJ Kim, M Yun - Nuclear Medicine and …, 2024 - Springer
Positron emission tomography/computed tomography (PET/CT) has dramatically altered the
landscape of noninvasive glioma evaluation, offering complementary insights to those …
landscape of noninvasive glioma evaluation, offering complementary insights to those …
[HTML][HTML] Concurrent Oncolysis and Neurolesion Repair by Dual Gene-Engineered hNSCs in an Experimental Model of Intraspinal Cord Glioblastoma
X Zeng, AE Ropper, Z Aljuboori, D Yu, TW Teng… - Cells, 2024 - mdpi.com
Intramedullary spinal cord glioblastoma (ISCG) is lethal due to lack of effective treatment. We
previously established a rat C6-ISCG model and the antitumor effect of F3. CD-TK, an hNSC …
previously established a rat C6-ISCG model and the antitumor effect of F3. CD-TK, an hNSC …
Simulating the impact of tumor mechanical forces on glymphatic networks in the brain parenchyma
The brain glymphatic system is currently being explored in the context of many neurological
disorders and diseases, including traumatic brain injury, Alzheimer's disease, and ischemic …
disorders and diseases, including traumatic brain injury, Alzheimer's disease, and ischemic …
Visualizing cancer-originating acetate uptake through monocarboxylate transporter 1 in reactive astrocytes in the glioblastoma tumor microenvironment
D Kim, HY Ko, JI Chung, YM Park, S Lee… - Neuro …, 2024 - academic.oup.com
Background Reactive astrogliosis is a hallmark of various brain pathologies, including
neurodegenerative diseases and glioblastomas. However, the specific intermediate …
neurodegenerative diseases and glioblastomas. However, the specific intermediate …
Integration of spatial transcriptomics with immunofluorescence staining reveals spatial heterogeneity and plasticity of astrocytes in experimental glioblastomas
Astrocytes comprise~ 50% of all brain cells and present distinct morphological, molecular
and functional properties in different brain regions. In glioblastoma (GBM), an aggressive …
and functional properties in different brain regions. In glioblastoma (GBM), an aggressive …
Smac Mimetic Compounds Engage Peripheral and Neuroimmune Action Against Glioblastoma
K Malone - 2024 - ruor.uottawa.ca
Abstract The Inhibitor of Apoptosis (IAP) proteins promote cell survival and are at the nexus
of multiple inflammatory pathways. Smac mimetic compounds (SMCs) are small molecule …
of multiple inflammatory pathways. Smac mimetic compounds (SMCs) are small molecule …