OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence
of calcification may change portions of the arterial conduit to a noncompliant structure …

Calcific aortic valve disease (CAVD) encompasses the range of disease from initial
alterations in the cell biology of the leaflets to end-stage calcification resulting in left …

The ACC and the AHA have long been involved in the joint development of practice
guidelines designed to assist healthcare providers in the management of selected …

The ACC and the AHA have long been involved in the joint development of practice
guidelines designed to assist healthcare providers in the management of selected …

with the matrix and with the periodicity of negative charges on collagen. Crystals initially
form octacalcium phosphate [Ca8H2 (PO4) 6· 5H2O], which reorganizes and seeds epitaxial …

ACE has been identified in aortic sclerotic lesions. 13 Although there is evidence that some
ACE may be produced locally, the majority was extracellular and colocalized with …

Background Calcific aortic stenosis has many characteristics in common with
atherosclerosis, including hypercholesterolemia. We hypothesized that intensive lipid …

ContextLipid-lowering agents are widely prescribed in the United States. Reliable estimates
of rhabdomyolysis risk with various lipid-lowering agents are not available. ObjectiveTo …

Cardiovascular calcification is a health disorder with increasing prevalence and high
morbidity and mortality. The only available therapeutic options for calcific vascular and …