The potential of cross-linking mass spectrometry in the development of protein–protein interaction modulators
Cross-linking mass spectrometry (XL-MS) can provide a wealth of information on
endogenous protein–protein interaction (PPI) networks and protein binding interfaces …
endogenous protein–protein interaction (PPI) networks and protein binding interfaces …
Chemical cross-linking and mass spectrometry enabled systems-level structural biology
L Botticelli, AA Bakhtina, NK Kaiser, A Keller… - Current Opinion in …, 2024 - Elsevier
Structural information on protein–protein interactions (PPIs) is essential for improved
understanding of regulatory interactome networks that confer various physiological and …
understanding of regulatory interactome networks that confer various physiological and …
Real-time spectral library matching for sample multiplexed quantitative proteomics
CD McGann, WD Barshop, JD Canterbury… - Journal of Proteome …, 2023 - ACS Publications
Sample multiplexed quantitative proteomics assays have proved to be a highly versatile
means to assay molecular phenotypes. Yet, stochastic precursor selection and precursor …
means to assay molecular phenotypes. Yet, stochastic precursor selection and precursor …
Advances in Mass Spectrometry‐Based Structural Proteomics: Development of HDX‐MS and XL‐MS Techniques from Recombinant Protein to Cellular Systems
VV Courouble, MD Mann… - Israel Journal of Chemistry, 2023 - Wiley Online Library
Mass spectrometry (MS) is a central analytical technique used to study proteins and
biomolecules. It measures mass‐to‐charge ratio of ions to identify and quantify molecules in …
biomolecules. It measures mass‐to‐charge ratio of ions to identify and quantify molecules in …
Autonomous Dissociation-type Selection for Glycoproteomics using a Real-Time Library Search
Tandem mass spectrometry (MS/MS) is the gold standard for intact glycopeptide
identification, enabling peptide sequence elucidation and site-specific localization of glycan …
identification, enabling peptide sequence elucidation and site-specific localization of glycan …