A recombinant fusion protein containing the domain III of the dengue-2 envelope protein is immunogenic and protective in nonhuman primates
L Hermida, L Bernardo, J Martín, M Alvarez, I Prado… - Vaccine, 2006 - Elsevier
We have previously reported the construction and evaluation in mice of recombinant fusion
proteins formed by a fragment (aa 286–426) of the dengue envelope protein and the P64k …
proteins formed by a fragment (aa 286–426) of the dengue envelope protein and the P64k …
Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K …
LJ González, PE Encinosa Guzmán… - Analytical and …, 2021 - Springer
A peptide from the P0 acidic ribosomal protein (pP0) of ticks conjugated to keyhole limpet
hemocyanin from Megathura crenulata has shown to be effective against different tick …
hemocyanin from Megathura crenulata has shown to be effective against different tick …
Towards the Immunoproteome of Neisseria meningitidis
TA Mendum, J Newcombe, CL McNeilly, J McFadden - PloS one, 2009 - journals.plos.org
Despite the introduction of conjugated polysaccharide vaccines for many of the Neisseria
meningitidis serogroups, neisserial infections continue to cause septicaemia and meningitis …
meningitidis serogroups, neisserial infections continue to cause septicaemia and meningitis …
Amino acid changes in the recombinant Dengue 3 Envelope domain III determine its antigenicity and immunogenicity in mice
A Zulueta, J Martín, L Hermida, M Alvarez, I Valdés… - Virus research, 2006 - Elsevier
The immunogenicity of the Envelope fragment from amino acid 284 to 426 of Dengue
viruses, obtained as fusion proteins with P64k in Escherichia coli, has been previously …
viruses, obtained as fusion proteins with P64k in Escherichia coli, has been previously …
Effect of conjugation methodology on the immunogenicity and protective efficacy of meningococcal group C polysaccharide–P64k protein conjugates
T Carmenate, L Canaán, A Álvarez… - FEMS Immunology & …, 2004 - academic.oup.com
Neisseria meningitidis serogroup C polysaccharide (CCPS) was conjugated to the carrier
protein P64k using two different conjugation procedures, condensation mediated by …
protein P64k using two different conjugation procedures, condensation mediated by …
A fragment of the envelope protein from dengue‐1 virus, fused in two different sites of the meningococcal P64k protein carrier, induces a functional immune response …
L Hermida, R Rodríguez, L Lazo… - Biotechnology and …, 2004 - Wiley Online Library
Previously we have reported the capacity of the fusion protein PD3, composed of the P64k
protein and the envelope (E) fragment from amino acids (aa) 286–426 of dengue‐2 virus …
protein and the envelope (E) fragment from amino acids (aa) 286–426 of dengue‐2 virus …
[HTML][HTML] Scaling-up fermentation of Escherichia coli for production of recombinant P64k protein from Neisseria meningitidis
RE Pérez, JG Suárez, EN Diaz, RS Rodríguez… - Electronic Journal of …, 2018 - Elsevier
Background P64k is a Neisseria meningitidis high molecular weight protein present in
meningococcal vaccine preparations. The lpdA gene, which encodes for this protein, was …
meningococcal vaccine preparations. The lpdA gene, which encodes for this protein, was …
P64k meningococcal protein as immunological carrier for weak immunogens
González, Alvarez, Caballero, Viña… - Scandinavian Journal …, 2000 - Wiley Online Library
Previously, the P64k meningococcal protein, an antigen of 64 kDa expressed in Escherichia
coli, has been extensively characterized. We have successfully conjugated several synthetic …
coli, has been extensively characterized. We have successfully conjugated several synthetic …
The fusion site of envelope fragments from each serotype of Dengue virus in the P64k protein, influence some parameters of the resulting chimeric constructs
To characterize the effect of the envelope fragment fusion site in the P64k protein from
Neisseria meningitidis several chimeric constructs were obtained. One variant consisted in …
Neisseria meningitidis several chimeric constructs were obtained. One variant consisted in …
Safety and preliminary immunogenicity of the recombinant outer membrane protein P64k of Neisseria meningitidis in human volunteers
A Pérez, F Dickinson, Z Cinza, A Ruíz… - Biotechnology and …, 2001 - Wiley Online Library
P64k is a meningococcal protein from Neisseria meningitidis that has been obtained by
recombinant DNA technology. Recombinant P64k has been extensively characterized by …
recombinant DNA technology. Recombinant P64k has been extensively characterized by …