Associations of polypharmacy and inappropriate medications with adverse outcomes in older adults with cancer: a systematic review and meta‐analysis

MR Mohamed, E Ramsdale, KP Loh, A Arastu… - The …, 2020 - academic.oup.com
Background Polypharmacy (PP) and potentially inappropriate medications (PIM) are highly
prevalent in older adults with cancer. This study systematically reviews the associations of …

A practical guide to geriatric syndromes in older adults with cancer: a focus on falls, cognition, polypharmacy, and depression

A Magnuson, S Sattar, G Nightingale… - American Society of …, 2019 - ascopubs.org
Geriatric syndromes are multifactorial conditions that are prevalent in older adults. Geriatric
syndromes are believed to develop when an individual experiences accumulated …

Systematic review and meta-analysis on the associations of polypharmacy and potentially inappropriate medication with adverse outcomes in older cancer patients

LJ Chen, K Trares, DC Laetsch… - The Journals of …, 2021 - academic.oup.com
Background Both polypharmacy and potentially inappropriate medication (PIM) intake are
highly prevailing in older cancer patients. However, only studies on the association of …

Polypharmacy in older adults undergoing major surgery: prevalence, association with postoperative cognitive dysfunction and potential associated anesthetic agents

S Lertkovit, A Siriussawakul, P Suraarunsumrit… - Frontiers in …, 2022 - frontiersin.org
Background Polypharmacy, which is defined as the use of 5 or more medications, can exert
significant adverse impact on older adult patients. The objective of this study was to …

Interventions to reduce polypharmacy and optimize medication use in older adults with cancer

A Barlow, ES Prusak, B Barlow… - Journal of geriatric …, 2021 - Elsevier
The use of polypharmacy and potentially inappropriate medications (PIMs) is an
increasingly common, concerning public health issue in older adults, and a concurrent …

Relationship between polypharmacy and inpatient hospitalization among older adults with cancer treated with intravenous chemotherapy

G Lu-Yao, G Nightingale, N Nikita, S Keith… - Journal of geriatric …, 2020 - Elsevier
Objectives Polypharmacy (≥ 5 concurrent medications) is common among older patients
with cancer (48%–80%) and associated with increased frailty, morbidity, and mortality. This …

Preoperative deprescribing for medical optimization of older adults undergoing surgery: a systematic review

JW Lee, M Li, CM Boyd, AR Green… - Journal of the American …, 2022 - Elsevier
Objective To summarize the evidence for preoperative deprescribing and its effect on
postoperative outcomes in older adults undergoing surgery. Design Systematic review …

Polypharmacy at admission prolongs length of hospitalization in gastrointestinal surgery patients

N Abe, T Kakamu, T Kumagai, T Hidaka… - Geriatrics & …, 2020 - Wiley Online Library
Aim Polypharmacy in elderly people is a social issue and has been reported to cause not
only drug adverse events, but also falls, dysfunction and cognitive decline. Those events …

The prevalence and factors associated with potentially inappropriate medication use in Chinese older outpatients with cancer with multimorbidity

F Tian, R Yang, Z Chen, X Duan, P Yuan - Journal of Geriatric Oncology, 2022 - Elsevier
Background Multimorbidity and polypharmacy is a general problem in older patients; they
increase the prevalence of potentially inappropriate medication (PIM) use. But PIM use in …

Potentially inappropriate medication use based on two deprescribing criteria and related factors in patients with terminal cancer: A cross-sectional study

S Kim, S Park, SH Yoo, KH Choi, JY Lee - Journal of Geriatric Oncology, 2023 - Elsevier
Introduction We aimed to estimate the nationwide prevalence of potentially inappropriate
medication (PIM) use in patients with terminal cancer according to two deprescribing criteria …