The impact and toxicity of glyphosate and glyphosate-based herbicides on health and immunity

C Peillex, M Pelletier - Journal of immunotoxicology, 2020 - Taylor & Francis
Glyphosate, or N-phosphomethyl (glycine), is an organophosphorus compound and a
competitive inhibitor of the shikimate pathway that allows aromatic amino acid biosynthesis …

Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment

J Parker, C O'brien, J Hawrelak, FL Gersh - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

[HTML][HTML] Indirect effects of the herbicide glyphosate on plant, animal and human health through its effects on microbial communities

AHC Van Bruggen, MR Finckh, M He… - Frontiers in …, 2021 - frontiersin.org
The herbicide glyphosate interferes with the shikimate pathway in plants and in major
groups of microorganisms impeding the production of aromatic amino acids. Glyphosate …

Impact of contaminants on microbiota: linking the gut–brain axis with neurotoxicity

J Balaguer-Trias, D Deepika, M Schuhmacher… - International Journal of …, 2022 - mdpi.com
Over the last years, research has focused on microbiota to establish a missing link between
neuronal health and intestine imbalance. Many studies have considered microbiota as …

Pleiotropic outcomes of glyphosate exposure: from organ damage to effects on inflammation, cancer, reproduction and development

M Marino, E Mele, A Viggiano, SL Nori… - International Journal of …, 2021 - mdpi.com
Glyphosate is widely used worldwide as a potent herbicide. Due to its ubiquitous use, it is
detectable in air, water and foodstuffs and can accumulate in human biological fluids and …

Endobolome, a new concept for determining the influence of microbiota disrupting chemicals (MDC) in relation to specific endocrine pathogenesis

M Aguilera, Y Gálvez-Ontiveros, A Rivas - Frontiers in microbiology, 2020 - frontiersin.org
Endogenous steroid hormones and Endocrine Disrupting Chemicals (EDC) interact with gut
microbiota through different pathways. We suggest the use of the term “endobolome” when …

The effect of pesticides on the microbiome of animals

MY Syromyatnikov, MM Isuwa, OV Savinkova… - Agriculture, 2020 - mdpi.com
In recent decades an increase in the use of pesticides to protect plants from pests, diseases
and weeds has been observed. There are many studies on the effects of various pesticides …

Glyphosate-based herbicides: Evidence of immune-endocrine alteration

A Maddalon, V Galbiati, C Colosio, S Mandić-Rajčević… - Toxicology, 2021 - Elsevier
Glyphosate (G) is the active ingredient of the most widely used herbicide products. It targets
the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which lacks in humans …

Pesticides and their impairing effects on epithelial barrier integrity, dysbiosis, disruption of the AhR signaling pathway and development of immune-mediated …

C Lima, MAP Falcão, JGS Rosa, GR Disner… - International Journal of …, 2022 - mdpi.com
The environmental and occupational risk we confront from agricultural chemicals increases
as their presence in natural habitats rises to hazardous levels, building a major part of the …

[HTML][HTML] MAIT cell activation is reduced by direct and microbiota-mediated exposure to bisphenols

JL Krause, B Engelmann, UN Da Rocha… - Environment …, 2022 - Elsevier
Oral uptake is the primary route of human bisphenol exposure, resulting in an exposure of
the intestinal microbiota and intestine-associated immune cells. Therefore, we compared the …