[HTML][HTML] COVID-19 and the chemical senses: supporting players take center stage
The main neurological manifestation of COVID-19 is loss of smell or taste. The high
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …
Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities
S SantaCruz-Calvo, L Bharath, G Pugh… - Nature Reviews …, 2022 - nature.com
Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to
decreases in physical activity levels and a shift to diets that include addictive and/or high …
decreases in physical activity levels and a shift to diets that include addictive and/or high …
Taste transduction and channel synapses in taste buds
A Taruno, K Nomura, T Kusakizako, Z Ma… - … -European Journal of …, 2021 - Springer
The variety of taste sensations, including sweet, umami, bitter, sour, and salty, arises from
diverse taste cells, each of which expresses specific taste sensor molecules and associated …
diverse taste cells, each of which expresses specific taste sensor molecules and associated …
[HTML][HTML] All-electrical Ca2+-independent signal transduction mediates attractive sodium taste in taste buds
K Nomura, M Nakanishi, F Ishidate, K Iwata, A Taruno - Neuron, 2020 - cell.com
Sodium taste regulates salt intake. The amiloride-sensitive epithelial sodium channel
(ENaC) is the Na+ sensor in taste cells mediating attraction to sodium salts. However, cells …
(ENaC) is the Na+ sensor in taste cells mediating attraction to sodium salts. However, cells …
[HTML][HTML] Molecular and cellular mechanisms of salt taste
Salt taste, the taste of sodium chloride (NaCl), is mechanistically one of the most complex
and puzzling among basic tastes. Sodium has essential functions in the body but causes …
and puzzling among basic tastes. Sodium has essential functions in the body but causes …
Serotonin regulates mitochondrial biogenesis and function in rodent cortical neurons via the 5-HT2A receptor and SIRT1–PGC-1α axis
SE Fanibunda, S Deb, B Maniyadath… - Proceedings of the …, 2019 - National Acad Sciences
Mitochondria in neurons, in addition to their primary role in bioenergetics, also contribute to
specialized functions, including regulation of synaptic transmission, Ca2+ homeostasis …
specialized functions, including regulation of synaptic transmission, Ca2+ homeostasis …
On the molecular nature of large-pore channels
J Syrjanen, K Michalski, T Kawate… - Journal of molecular …, 2021 - Elsevier
Membrane transport is a fundamental means to control basic cellular processes such as
apoptosis, inflammation, and neurodegeneration and is mediated by a number of …
apoptosis, inflammation, and neurodegeneration and is mediated by a number of …
[HTML][HTML] Recent advances in taste transduction and signaling
SC Kinnamon, TE Finger - F1000Research, 2019 - ncbi.nlm.nih.gov
In the last few years, single-cell profiling of taste cells and ganglion cells has advanced our
understanding of transduction, encoding, and transmission of information from taste buds as …
understanding of transduction, encoding, and transmission of information from taste buds as …
Molecular insights into human taste perception and umami tastants: A review
J Diepeveen, TCW Moerdijk‐Poortvliet… - Journal of Food …, 2022 - Wiley Online Library
Understanding taste is key for optimizing the palatability of seaweeds and other non‐animal‐
based foods rich in protein. The lingual papillae in the mouth hold taste buds with taste …
based foods rich in protein. The lingual papillae in the mouth hold taste buds with taste …
Sour taste: receptors, cells and circuits
ER Liman, SC Kinnamon - Current opinion in physiology, 2021 - Elsevier
Sour taste, which is evoked by low pH, is one of the original four fundamental taste qualities,
recognized as a distinct taste sensation for centuries, and universally aversive across …
recognized as a distinct taste sensation for centuries, and universally aversive across …