Many animal models have been developed to study the causes and treatments of chronic
kidney disease (CKD) in humans, an insidious disease resulting from kidney injury and …

Chronic kidney disease (CKD) is a global health concern and public health priority. The
condition often involves inflammation due to the accumulation of toxins and the reduced …

With increasing prevalence, chronic kidney disease (CKD) has become a global health
problem. Due to the retention of uremic toxins, electrolytes and water, and the resultant …

Diabetic kidney disease (DKD) represents an enormous burden in patients with type 2
diabetes mellitus (T2DM). Preclinical studies using most glucose-lowering agents have …

The pathogenesis of crystal nephropathy involves deposition of intratubular crystals, tubular
obstruction and cell death. The deposition of 8-dihydroxyadenine (DHA) crystals within …

Cardiovascular autonomic dysfunction is a major complication of chronic kidney disease
(CKD), likely contributing to the high incidence of cardiovascular mortality in this patient …

Fibrosis is often the end result of chronic inflammation. It is characterized by the excessive
deposition of extracellular matrix. This leads to structural alterations in the tissue, causing …

The aim of the present study was to assess the short-term effects of Thymoquinone (TQ) on
oxidative stress, glycaemic control, and renal functions in diabetic rats. DM was induced in …

Many foods contain rutin, a flavonoid with many health benefits. Here we tested rutin to
reverse chronic kidney disease (CKD) and associated cardiovascular disease, using an …

Glibenclamide (GLB), most widely used in the treatment of type II diabetes mellitus, inhibits
K+ ATP channel in pancreatic-β cells and releases insulin, while thioacetamide (TAA) is a …