Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …

Chronic kidney disease (CKD) patients often exhibit a low muscle mass and strength,
leading to physical impairment and an increased mortality. Two major signalling pathways …

Purpose Regular resistance exercise training and a balanced diet may counteract the age-
related muscular decline on a molecular level. The aim of this study was to investigate the …

Background Myostatin is a protein synthesized and secreted by skeletal muscle that
negatively regulates muscle mass. The extent to which circulating myostatin levels change …

The normal development and function of photoreceptors is essential for eye health and
visual acuity in vertebrates. Mutations in genes encoding proteins involved in photoreceptor …

The age-related loss of skeletal muscle (sarcopenia) is a major health concern as it is
associated with physical disability, metabolic impairments, and increased mortality. The …

Muscle wasting, known to develop in patients with chronic kidney disease (CKD), is a
deleterious consequence of numerous complications associated with deteriorated renal …

Sarcopenia, characterized by low muscle mass and function, results in frailty, comorbidities
and mortality. However, its prevalence varies according to the different criteria used in its …

Musculoskeletal diseases are highly prevalent with staggering annual health care costs
across the globe. The combined wasting of muscle (sarcopenia) and bone (osteoporosis) …

Background Myostatin, its inhibitor follistatin, and growth/differentiation factor 11 (GDF11)
have been proposed as factors that could potentially modify biological aging. The study …