Homeodomain proteins: an update

TR Bürglin, M Affolter - Chromosoma, 2016 - Springer
Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …

Nf2/Merlin: a coordinator of receptor signalling and intercellular contact

M Curto, AI McClatchey - British journal of cancer, 2008 - nature.com
This review explores possible mechanisms by which the neurofibromatosis type-2 tumour
suppressor Merlin regulates contact-dependent inhibition of proliferation. Starting from an …

PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors

H Cui, A Hayashi, HS Sun, MP Belmares… - Journal of …, 2007 - Soc Neuroscience
In neuronal synapses, PDZ domains [postsynaptic density-95 (PSD-95)/Discs large/zona
occludens-1] of PSD-95 proteins interact with C termini of NMDA receptor [NMDAR (NR)] …

Identification of FOXO targets that generate diverse features of the diapause phenotype in the mosquito Culex pipiens

C Sim, DS Kang, S Kim, X Bai… - Proceedings of the …, 2015 - National Acad Sciences
Insulin and juvenile hormone signaling direct entry of the mosquito Culex pipiens into its
overwintering adult diapause, and these two critical signaling pathways appear to do so by …

Nucleocytoplasmic functions of the PDZ‐LIM protein family: new insights into organ development

J Krcmery, T Camarata, A Kulisz, HG Simon - Bioessays, 2010 - Wiley Online Library
Recent work on the PDZ‐LIM protein family has revealed that it has important activities at the
cellular level, mediating signals between the nucleus and the cytoskeleton, with significant …

Zasp is required for the assembly of functional integrin adhesion sites

K Jani, F Schöck - The Journal of cell biology, 2007 - rupress.org
The integrin family of heterodimeric transmembrane receptors mediates cell–matrix
adhesion. Integrins often localize in highly organized structures, such as focal adhesions in …

Loss of microRNA-17∼ 92 in smooth muscle cells attenuates experimental pulmonary hypertension via induction of PDZ and LIM domain 5

T Chen, G Zhou, Q Zhou, H Tang, JCF Ibe… - American journal of …, 2015 - atsjournals.org
Rationale: Recent studies suggest that microRNAs (miRNAs) play important roles in
regulation of pulmonary artery smooth muscle cell (PASMC) phenotype and are implicated …

A class III PDZ binding motif in the myotilin and FATZ families binds enigma family proteins: a common link for Z-disc myopathies

P von Nandelstadh, M Ismail, C Gardin… - … and cellular biology, 2009 - Taylor & Francis
Interactions between Z-disc proteins regulate muscle functions and disruption of these
interactions results in muscle disorders. Mutations in Z-disc components myotilin …

PDZ and LIM domain‐encoding genes: molecular interactions and their role in development

AJW Te Velthuis, CP Bagowski - The Scientific World Journal, 2007 - Wiley Online Library
PDZ/LIM genes encode a group of proteins that play very important, but diverse, biological
roles. They have been implicated in numerous vital processes, eg, cytoskeleton …

ALP/Enigma PDZ–LIM domain proteins in the heart

M Zheng, H Cheng, I Banerjee… - Journal of molecular cell …, 2010 - academic.oup.com
Actinin-associated LIM protein (ALP) and Enigma are two subfamilies of Postsynaptic
density 95, discs large and zonula occludens-1 (PDZ)–Lin-11, Isl1 and Mec-3 (LIM) domain …