[HTML][HTML] From bacteria to biomedicine: Developing therapies exploiting NAD+ metabolism

Y Chen, Y Ying, J Lalsiamthara, Y Zhao, S Imani… - Bioorganic …, 2023 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) serves as a critical cofactor in cellular
metabolism and redox reactions. Bacterial pathways rely on NAD+ participation, where its …

Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones

TH Dao, H Echlin, A McKnight, ES Marr, J Junker, Q Jia… - Mbio, 2024 - Am Soc Microbiol
Streptococcus pneumoniae is a major human pathogen of global health concern and the
rapid emergence of antibiotic resistance poses a serious public health problem worldwide …