[HTML][HTML] Current perspectives on “off-the-shelf” allogeneic NK and CAR-NK cell therapies
EL Heipertz, ER Zynda, TE Stav-Noraas… - Frontiers in …, 2021 - frontiersin.org
Natural killer cells (NK cells) are the first line of the innate immune defense system, primarily
located in peripheral circulation and lymphoid tissues. They kill virally infected and …
located in peripheral circulation and lymphoid tissues. They kill virally infected and …
[HTML][HTML] Exosomes: A potential tool for immunotherapy of ovarian cancer
X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …
[HTML][HTML] Allogeneic CAR T cells: an alternative to overcome challenges of CAR T cell therapy in glioblastoma
D Martínez Bedoya, V Dutoit, D Migliorini - Frontiers in immunology, 2021 - frontiersin.org
Chimeric antigen receptor (CAR) T cell therapy has emerged as one of the major
breakthroughs in cancer immunotherapy in the last decade. Outstanding results in …
breakthroughs in cancer immunotherapy in the last decade. Outstanding results in …
CXCR4 and anti-BCMA CAR co-modified natural killer cells suppress multiple myeloma progression in a xenograft mouse model
The highly restricted expression of B-cell maturation antigen (BCMA) on plasma cells makes
it an ideal target for chimeric antigen receptor (CAR) immune cell therapy against multiple …
it an ideal target for chimeric antigen receptor (CAR) immune cell therapy against multiple …
[HTML][HTML] Current targeted therapy for metastatic colorectal cancer
T Ohishi, MK Kaneko, Y Yoshida, A Takashima… - International journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is the third most common type of cancer and the second leading
cause of cancer deaths worldwide. Surgery or surgery plus radiotherapy and/or …
cause of cancer deaths worldwide. Surgery or surgery plus radiotherapy and/or …
[HTML][HTML] CAR-NKT cell therapy: a new promising paradigm of cancer immunotherapy
Today, cancer treatment is one of the fundamental problems facing clinicians and
researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new …
researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new …
Targeting immune checkpoints: how to use natural killer cells for fighting against solid tumors
F Ghaedrahmati, N Esmaeil… - Cancer …, 2023 - Wiley Online Library
Natural killer (NK) cells are unique innate immune cells that mediate anti‐viral and anti‐
tumor responses. Thus, they might hold great potential for cancer immunotherapy. NK cell …
tumor responses. Thus, they might hold great potential for cancer immunotherapy. NK cell …
Enhanced anti-tumor efficacy of IL-7/CCL19-producing human CAR-T cells in orthotopic and patient-derived xenograft tumor models
S Goto, Y Sakoda, K Adachi, Y Sekido, S Yano… - Cancer Immunology …, 2021 - Springer
Chimeric antigen receptor (CAR)-T cell therapy has impressive efficacy in hematological
malignancies, but its application in solid tumors remains a challenge. Multiple hurdles …
malignancies, but its application in solid tumors remains a challenge. Multiple hurdles …
Multiparameter longitudinal imaging of immune cell activity in chimeric antigen receptor T cell and checkpoint blockade therapies
Longitudinal multimodal imaging presents unique opportunities for noninvasive surveillance
and prediction of treatment response to cancer immunotherapy. In this work we first …
and prediction of treatment response to cancer immunotherapy. In this work we first …
Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level
L Zhang, P Liu, Y Jiang, D Fan, X He, J Zhang… - European Journal of …, 2024 - Elsevier
Colorectal cancer (CRC) is trending to be a major health problem throughout the world.
Therapeutics with dual modes of action have shown latent capacity to create ideal anti-tumor …
Therapeutics with dual modes of action have shown latent capacity to create ideal anti-tumor …