Experimental and clinical biomarkers for progressive evaluation of neuropathology and therapeutic interventions for acute and chronic neurological disorders

DS Reddy, HN Abeygunaratne - International Journal of Molecular …, 2022 - mdpi.com
This article describes commonly used experimental and clinical biomarkers of neuronal
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …

Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin

S Nurdiana, YM Goh, H Ahmad, SM Dom… - … and alternative medicine, 2017 - Springer
Background The potential application of Ficus deltoidea and vitexin for the management of
symptomatologies associated with diabetes mellitus (DM) has gained much attention …

Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex …

MH Sarikahya, SL Cousineau, M De Felice… - Molecular …, 2023 - nature.com
With increasing maternal cannabis use, there is a need to investigate the lasting impact of
prenatal exposure to Δ9-tetrahydrocannabinol (THC), the main psychotropic compound in …

Vitamin D3 supplementation ameliorates cognitive impairment and alters neurodegenerative and inflammatory markers in scopolamine induced rat model

P Patel, J Shah - Metabolic Brain Disease, 2022 - Springer
A multifaceted approach can be effective for the treatment of dementia including the most
common form, Alzheimer's disease (AD). However, currently, it involves only symptomatic …

Short-term omega-3 supplementation modulates novel neurovascular and fatty acid metabolic proteome changes in the retina and ophthalmic artery of mice with …

N Perumal, A Herfurth, N Pfeiffer, C Manicam - Cells, 2022 - mdpi.com
Cytochrome P450 (CYP) gene mutations are a common predisposition associated with
glaucoma. Although the molecular mechanisms are largely unknown, omega-3 …

Omega-3 fatty acid-type docosahexaenoic acid protects against Aβ-mediated mitochondrial deficits and pathomechanisms in Alzheimer's disease-related animal …

YH Park, SJ Shin, HS Kim, SB Hong, S Kim… - International Journal of …, 2020 - mdpi.com
It has been reported that damage to the mitochondria affects the progression of Alzheimer's
disease (AD), and that mitochondrial dysfunction is improved by omega-3. However, no …

[HTML][HTML] Improvement of spatial learning and memory, cortical gyrification patterns and brain oxidative stress markers in diabetic rats treated with Ficus deltoidea leaf …

S Nurdiana, YM Goh, A Hafandi, SM Dom… - Journal of Traditional …, 2018 - Elsevier
Despite the fact that Ficus deltoidea and vitexin played important roles in controlling
hyperglycemia, an effective mitigation strategy dealing with cognitive deficit observed in …

[HTML][HTML] Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse …

BS Alghamdi, HA AboTaleb - Journal of Integrative Neuroscience, 2020 - imrpress.com
Multiple sclerosis is a progressive autoimmune disorder of the myelin sheath and is the most
common inflammatory disease of young adults. Up to 65% of multiple sclerosis patients …

Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates …

HCS Abeysinghe, L Bokhari, A Quigley… - Stem Cell Research & …, 2015 - Springer
Introduction Despite attempts to prevent brain injury during the hyperacute phase of stroke,
most sufferers end up with significant neuronal loss and functional deficits. The use of cell …

Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function

SR Archie, AE Sifat, D Mara, Y Ahn, KA Akter… - Frontiers in …, 2023 - frontiersin.org
Introduction: Despite the prevalence of the perception that electronic cigarettes (e-cig) are a
safer alternative to tobacco smoke, growing concern about their potential toxic impact …