Future‐oriented advanced diarylethene photoswitches: from molecular design to spontaneous assembly systems

HB Cheng, S Zhang, E Bai, X Cao, J Wang… - Advanced …, 2022 - Wiley Online Library
Diarylethene (DAE) photoswitch is a new and promising family of photochromic molecules
and has shown superior performance as a smart trigger in stimulus‐responsive materials …

Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

JM Dąbrowski, LG Arnaut - Photochemical & Photobiological Sciences, 2015 - pubs.rsc.org
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and
adequate use of both to trigger biological mechanisms that can rapidly destroy the primary …

Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

JM Dąbrowski, B Pucelik, A Regiel-Futyra… - Coordination Chemistry …, 2016 - Elsevier
Applications of metalloporphyrins and related molecules have been extensively pursued in
the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This …

Construction of nanomaterials with targeting phototherapy properties to inhibit resistant bacteria and biofilm infections

Y Wang, Y Jin, W Chen, J Wang, H Chen, L Sun… - Chemical Engineering …, 2019 - Elsevier
The spread of resistant bacteria and the development bacterial biofilm have been two major
challenges in the application of biomaterials, causing device failure as well as tissue …

Oxygen-generating hybrid nanoparticles to enhance fluorescent/photoacoustic/ultrasound imaging guided tumor photodynamic therapy

S Gao, G Wang, Z Qin, X Wang, G Zhao, Q Ma, L Zhu - Biomaterials, 2017 - Elsevier
Photodynamic therapy (PDT) is a promising tumor treatment modality that can convert
oxygen into cytotoxic singlet oxygen (SO) via photosensitizer to ablate tumor growth …

In vitro demonstration of the heavy-atom effect for photodynamic therapy

A Gorman, J Killoran, C O'Shea, T Kenna… - Journal of the …, 2004 - ACS Publications
Photodynamic therapy (PDT) is an emerging treatment modality for a range of disease
classes, both cancerous and noncancerous. This has brought about an active pursuit of new …

Reactive oxygen species in photodynamic therapy: mechanisms of their generation and potentiation

JM Dąbrowski - Advances in inorganic chemistry, 2017 - Elsevier
Reactive oxygen species (ROS) play key roles in cell signaling systems and homeostasis,
and they are also fundamental to photodynamic therapy (PDT). PDT efficacy can be affected …

Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia

H Ding, H Yu, Y Dong, R Tian, G Huang… - Journal of Controlled …, 2011 - Elsevier
Photodynamic therapy (PDT) is an emerging clinical modality for the treatment of a variety of
diseases. Most photosensitizers are hydrophobic and poorly soluble in water. Many new …

Overcoming the challenges of infrared photosensitizers in photodynamic therapy: The making of redaporfin

LG Arnaut, MM Pereira - Chemical Communications, 2023 - pubs.rsc.org
We offer a personal account of the discovery and development of a photosensitizer for
photodynamic therapy (PDT) of cancer, from bench to bedside. We emphasize the more …