Burkholderia pseudomallei and melioidosis
EM Meumann, D Limmathurotsakul… - Nature Reviews …, 2024 - nature.com
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of
tropical and subtropical regions globally. Modelled estimates of the global burden predict …
tropical and subtropical regions globally. Modelled estimates of the global burden predict …
[HTML][HTML] Melioidosis
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …
Within-host evolution of bacterial pathogens
Whole-genome sequencing has opened the way for investigating the dynamics and
genomic evolution of bacterial pathogens during the colonization and infection of humans …
genomic evolution of bacterial pathogens during the colonization and infection of humans …
Population genomics of bacterial host adaptation
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …
Indeed, an estimated 60% of all human pathogens have originated from other animal …
[HTML][HTML] Bacterial stress responses during host infection
Pathogenic bacteria must withstand diverse host environments during infection.
Environmental signals, such as pH, temperature, nutrient limitation, etc., not only trigger …
Environmental signals, such as pH, temperature, nutrient limitation, etc., not only trigger …
Gut microbes may facilitate insect herbivory of chemically defended plants
The majority of insect species consume plants, many of which produce chemical toxins that
defend their tissues from attack. How then are herbivorous insects able to develop on a …
defend their tissues from attack. How then are herbivorous insects able to develop on a …
[HTML][HTML] Melioidosis diagnostic workshop, 2013
AR Hoffmaster, D AuCoin, P Baccam… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a severe disease that can be difficult to diagnose because of its diverse
clinical manifestations and a lack of adequate diagnostic capabilities for suspected cases …
clinical manifestations and a lack of adequate diagnostic capabilities for suspected cases …
Human melioidosis
I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …
endemic in Southeast Asia and northern Australia, with increased incidence associated with …
[HTML][HTML] Efflux pump-mediated drug resistance in Burkholderia
NL Podnecky, KA Rhodes, HP Schweizer - Frontiers in microbiology, 2015 - frontiersin.org
Several members of the genus Burkholderia are prominent pathogens. Infections caused by
these bacteria are difficult to treat because of significant antibiotic resistance. Virtually all …
these bacteria are difficult to treat because of significant antibiotic resistance. Virtually all …
[HTML][HTML] Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis
RL Houghton, DE Reed, MA Hubbard… - PLoS neglected …, 2014 - journals.plos.org
Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of
melioidosis. Isolation of B. pseudomallei from clinical samples is the “gold standard” for the …
melioidosis. Isolation of B. pseudomallei from clinical samples is the “gold standard” for the …