Burkholderia pseudomallei and melioidosis

EM Meumann, D Limmathurotsakul… - Nature Reviews …, 2024 - nature.com
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of
tropical and subtropical regions globally. Modelled estimates of the global burden predict …

[HTML][HTML] Melioidosis

WJ Wiersinga, HS Virk, AG Torres, BJ Currie… - Nature reviews Disease …, 2018 - nature.com
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …

Within-host evolution of bacterial pathogens

X Didelot, AS Walker, TE Peto, DW Crook… - Nature Reviews …, 2016 - nature.com
Whole-genome sequencing has opened the way for investigating the dynamics and
genomic evolution of bacterial pathogens during the colonization and infection of humans …

Population genomics of bacterial host adaptation

SK Sheppard, DS Guttman, JR Fitzgerald - Nature Reviews Genetics, 2018 - nature.com
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …

[HTML][HTML] Bacterial stress responses during host infection

FC Fang, ER Frawley, T Tapscott, A Vázquez-Torres - Cell host & microbe, 2016 - cell.com
Pathogenic bacteria must withstand diverse host environments during infection.
Environmental signals, such as pH, temperature, nutrient limitation, etc., not only trigger …

Gut microbes may facilitate insect herbivory of chemically defended plants

TJ Hammer, MD Bowers - Oecologia, 2015 - Springer
The majority of insect species consume plants, many of which produce chemical toxins that
defend their tissues from attack. How then are herbivorous insects able to develop on a …

[HTML][HTML] Melioidosis diagnostic workshop, 2013

AR Hoffmaster, D AuCoin, P Baccam… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a severe disease that can be difficult to diagnose because of its diverse
clinical manifestations and a lack of adequate diagnostic capabilities for suspected cases …

Human melioidosis

I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

[HTML][HTML] Efflux pump-mediated drug resistance in Burkholderia

NL Podnecky, KA Rhodes, HP Schweizer - Frontiers in microbiology, 2015 - frontiersin.org
Several members of the genus Burkholderia are prominent pathogens. Infections caused by
these bacteria are difficult to treat because of significant antibiotic resistance. Virtually all …

[HTML][HTML] Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis

RL Houghton, DE Reed, MA Hubbard… - PLoS neglected …, 2014 - journals.plos.org
Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of
melioidosis. Isolation of B. pseudomallei from clinical samples is the “gold standard” for the …