A review on the phytochemistry, medicinal properties and pharmacological activities of 15 selected Myanmar medicinal plants

MM Aye, HT Aung, MM Sein, C Armijos - Molecules, 2019 - mdpi.com
Medicinal plants are a reservoir of biologically active compounds with therapeutic properties
that over time have been reported and used by diverse groups of people for treatment of …

Natural products and synthetic analogs as a source of antitumor drugs

J Sharifi-Rad, A Ozleyen, T Boyunegmez Tumer… - Biomolecules, 2019 - mdpi.com
Cancer is a heterogeneous disease and one of the major issues of health concern,
especially for the public health system globally. Nature is a source of anticancer drugs with …

Marine sponge natural products with anticancer potential: An updated review

C Calcabrini, E Catanzaro, A Bishayee, E Turrini… - Marine drugs, 2017 - mdpi.com
Despite the huge investment into research and the significant effort and advances made in
the search for new anticancer drugs in recent decades, cancer cure and treatment continue …

Strategies to target the Hedgehog signaling pathway for cancer therapy

M Xin, X Ji, LK De La Cruz, S Thareja… - Medicinal Research …, 2018 - Wiley Online Library
Hedgehog (Hh) signaling is an essential pathway in the human body, and plays a major role
in embryo development and tissue patterning. Constitutive activation of the Hh signaling …

Computational guided identification of potential leads from Acacia pennata (L.) Willd. as inhibitors for cellular entry and viral replication of SARS-CoV-2

JH Zothantluanga, N Gogoi, A Shakya, D Chetia… - Future Journal of …, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) started in 2019 and is still an on-going …

[PDF][PDF] Antimalarial flavonoid-glycoside from acacia pennata with inhibitory potential against PfDHFR-TS: an in-silico study

JH Zothantluanga, SK Aswin, M Rudrapal… - Biointerface Res. Appl …, 2021 - researchgate.net
Drug resistance, toxicity, and adverse effects of current antimalarial drugs have mandated
the need to search for newer antimalarial agents. The present study aims to identify …

Phytochemicals for the prevention and treatment of pancreatic cancer: Current progress and future prospects

N Casarcia, P Rogers, E Guld, S Iyer… - British Journal of …, 2023 - Wiley Online Library
Pancreatic cancer is the third leading cause of cancer‐related deaths in the United States,
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …

Inventory of human-edible products from native Acacia sensu lato in Africa, America, and Asia: Spotlight on Senegalia seeds, overlooked wild legumes in the arid …

MS Drabo, H Shumoy, A Savadogo, K Raes - Food Research International, 2022 - Elsevier
Acacia sl. is a newly revised genus whose plant species are quintessential in the
pantropical, arid, and hunger-prone areas. They provide multiple ecosystem services and a …

Design of Hedgehog pathway inhibitors for cancer treatment

J Bariwal, V Kumar, Y Dong… - Medicinal research …, 2019 - Wiley Online Library
Hedgehog (Hh) signaling is involved in the initiation and progression of various cancers and
is essential for embryonic and postnatal development. This pathway remains in the …

Current trends in Hedgehog signaling pathway inhibition by small molecules

F Ghirga, M Mori, P Infante - Bioorganic & Medicinal Chemistry Letters, 2018 - Elsevier
Abstract The Hedgehog (Hh) signaling pathway is a widely appreciated target for anticancer
therapy. However, drug resistance at the Smoothened receptor (SMO) and Hh activation …