Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

The use of molecular tools to detect and type Leishmania species in humans, reservoirs or
sandflies has been pursued using different approaches. The polymerase chain reaction …

Background A century after its discovery, Chagas disease still represents a major neglected
tropical threat. Accurate diagnostics tools as well as surrogate markers of parasitological …

Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of
Latin America. Although the occurrence of acute cases sharply has declined due to …

Objectives: This prospective study focused on the evaluation of anti-parasitic therapy in
congenital Chagas' disease, diagnosed and monitored by PCR and conventional diagnosis …

Quantitative real-time PCR (qPCR) is an accurate method to quantify Trypanosoma cruzi
DNA and can be used to follow-up parasitemia in Chagas disease (CD) patients undergoing …

In the acute phase and in the chronic forms of Chagas disease, the etiological diagnosis
may be performed by detection of the parasite using direct or indirect parasitological …

The polymerase chain reaction (PCR) is a potentially interesting diagnostic tool for detecting
congenital Trypanosoma cruzi infection at birth. We have compared the sensitivity and …

Heart transplantation (HTx) is a useful therapy for end-stage Chagaś cardiomyopathy;
however, Chagas reactivation remains a mayor complication. Parasitological methods offer …

We have investigated the antiproliferative effects of SCH 56592, a new experimental
triazole, against Trypanosoma (Schizotrypanum) cruzi, the etiological agent of Chagas' …