mRNA-based therapeutics: powerful and versatile tools to combat diseases
S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
Progress in understanding the role of lncRNA in programmed cell death
N Jiang, X Zhang, X Gu, X Li, L Shang - Cell death discovery, 2021 - nature.com
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not
translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as …
translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as …
LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma
Y Liu, M Shi, X He, Y Cao, P Liu, F Li, S Zou… - Journal of Hematology & …, 2022 - Springer
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated
macrophages (TAMs). In this study, we found the function and molecular mechanism of …
macrophages (TAMs). In this study, we found the function and molecular mechanism of …
[HTML][HTML] Long non-coding RNAs and microRNAs interplay in osteogenic differentiation of mesenchymal stem cells
C Lanzillotti, M De Mattei, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) have gained great attention as epigenetic regulators of
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …
Recent updates on mechanisms of resistance to 5-fluorouracil and reversal strategies in colon cancer treatment
S Azwar, HF Seow, M Abdullah, M Faisal Jabar… - Biology, 2021 - mdpi.com
Simple Summary Acquired resistance to chemotherapy by cancer cells is the predominant
factor in chemotherapy failure, which ultimately leads to disease progression and death …
factor in chemotherapy failure, which ultimately leads to disease progression and death …
The Role of non-coding RNAs in colorectal cancer, with a focus on its autophagy
L Chen, M He, M Zhang, Q Sun, S Zeng, H Zhao… - Pharmacology & …, 2021 - Elsevier
Colorectal cancer (CRC) is one of malignant afflictions burdening people worldwide, mainly
caused by shortages of effective medical intervention and poorly mechanistic understanding …
caused by shortages of effective medical intervention and poorly mechanistic understanding …
Loss of cancer-associated fibroblast-derived exosomal DACT3-AS1 promotes malignant transformation and ferroptosis-mediated oxaliplatin resistance in gastric …
X Qu, B Liu, L Wang, L Liu, W Zhao, C Liu, J Ding… - Drug Resistance …, 2023 - Elsevier
Abstract Aims Long non-coding RNAs (lncRNAs), as one of the components of exosomes
derived from cancer-associated fibroblasts (CAFs), exhibit a crucial role in the pathogenesis …
derived from cancer-associated fibroblasts (CAFs), exhibit a crucial role in the pathogenesis …
MALAT1-related signaling pathways in colorectal cancer
WW Xu, J Jin, X Wu, QL Ren, M Farzaneh - Cancer cell international, 2022 - Springer
Colorectal cancer (CRC) is one of the most lethal and prevalent solid malignancies
worldwide. There is a great need of accelerating the development and diagnosis of CRC …
worldwide. There is a great need of accelerating the development and diagnosis of CRC …
The dynamism of transposon methylation for plant development and stress adaptation
Plant development processes are regulated by epigenetic alterations that shape nuclear
structure, gene expression, and phenotypic plasticity; these alterations can provide the plant …
structure, gene expression, and phenotypic plasticity; these alterations can provide the plant …
Mechanisms of taxane resistance
SM Maloney, CA Hoover, LV Morejon-Lasso… - Cancers, 2020 - mdpi.com
Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …