The poor prognosis and rising incidence of esophageal cancer highlight the need for
improved detection and prediction methods that are essential prior to treatment. Esophageal …

A thorough understanding of the tumor environment and underlying genetic factors helps in
the better formulation of cancer management strategies. Availability of efficient diagnostic …

Background microRNAs (miRNAs) are short non-coding RNAs that fine-tune gene
expression. The aberrant expression of miRNAs is associated with many diseases and they …

Radiation therapy controls local disease but also prompts the release of tumor-associated
antigens and stress-related danger signals that primes T cells to promote tumor regression …

MicroRNAs (miRNAs) are proposed as a family of short noncoding molecules able to
manage and control the expression of the gene targets at the posttranscriptional level. They …

Background and purpose With currently available techniques, the prediction of pathologic
complete response after neoadjuvant chemoradiotherapy is insufficient. The tumor-stroma …

The altered expression of miRNAs is involved in carcinogenesis of esophageal squamous
cell carcinoma (ESCC), but whether miRNAs regulate COX-2 expression in ESCC is not …

Chemotherapy is one of the options for cancer treatment. FOLFOX is one of the widely used
chemotherapeutic regimens used to treat primarily colorectal cancer and other cancers as …

Background A pathologically complete response (pCR) to neoadjuvant chemoradiotherapy
(nCRT) is seen in 30% of the patients with oesophageal cancer. The aim is to identify patient …

Patients with advanced esophageal cancer (T3-4, N) have a poor prognosis.
Chemoradiation or chemotherapy before esophagectomy with adequate lymphadenectomy …