Diagnosis and investigation of suspected haemophagocytic lymphohistiocytosis in adults: 2023 hyperinflammation and HLH across speciality collaboration (HiHASC) …

MF Cox, S Mackenzie, R Low, M Brown… - The Lancet …, 2024 - thelancet.com
Haemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome
characterised by persistently activated cytotoxic lymphocytes and macrophages, which, if …

Malignancy-associated hemophagocytic lymphohistiocytosis in Sweden: incidence, clinical characteristics, and survival

A Löfstedt, M Jädersten, M Meeths, JI Henter - Blood, 2024 - ashpublications.org
We evaluated malignancy-associated hemophagocytic lymphohistiocytosis (mal-HLH) in
Sweden regarding population-based incidence, clinical features, and survival. From 1997 to …

sCD25 as an independent adverse prognostic factor in adult patients with HLH: results of a multicenter retrospective study

T Wimmer, R Mattes, HJ Stemmler, F Hauck… - Blood …, 2023 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is a rare but often fatal hyperinflammatory
syndrome caused by an inborn or acquired error of immunity. In adults, the underlying …

Mortality and associated causes in hemophagocytic lymphohistiocytosis: a multiple-cause-of-death analysis in France

S La Marle, G Richard-Colmant, M Fauvernier… - Journal of Clinical …, 2023 - mdpi.com
Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome with
an overall mortality rate of 40%. A multiple-cause-of-death analysis allows for the …

Temporal trends in the incidence of hemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003–2018

J West, P Stilwell, H Liu, L Ban, M Bythell, TR Card… - …, 2022 - journals.lww.com
Hemophagocytic lymphohistiocytosis (HLH) is rare, results in high mortality, and is
increasingly being diagnosed. We aimed to quantify the incidence of diagnosed HLH and …

Case report: Hemophagocytic lymphohistiocytosis complicated by multiple organ dysfunction syndrome following aseptic encephalitis

QT Chen, MH Chen, YK Lin, RH Yeh, CC Lu… - Frontiers in …, 2023 - frontiersin.org
Hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially life-threatening
condition caused by excessive immune activation. Secondary HLH is usually triggered by …

1-year survival in haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003–2018

J West, P Stilwell, H Liu, L Ban, M Bythell… - Journal of Hematology & …, 2023 - Springer
Haemophagocytic lymphohistiocytosis (HLH) is a lethal syndrome of excessive immune
activation. We undertook a nationwide study in England of all cases of HLH diagnosed …

“A Dangerous Black Box:” Idiopathic Hemophagocytic Lymphohistiocytosis in Adult Patients—A Case Report and Review of the Literature

N Agbariah, J Sanz, A Rovó - Case reports in hematology, 2022 - Wiley Online Library
Hemophagocytic lymphohistiocytosis (HLH) is a rare potentially life‐threatening condition
characterized by aberrant inflammation that can be related to genetic or sporadic forms. In …

Tuberculosis-associated hemophagocytic lymphohistiocytosis: diagnostic challenges and determinants of outcome

L Kurver, T Seers, S van Dorp… - Open Forum …, 2024 - academic.oup.com
Background Tuberculosis (TB) can induce secondary hemophagocytic lymphohistiocytosis
(HLH), a severe inflammatory syndrome with high mortality. We integrated all published …

Hemophagocytic lymphohistiocytosis associated with acute otitis media: A case report

DH Chung, KY Lee, JY Kim - Medicine, 2024 - journals.lww.com
Interventions: Aggressive treatment by using combination therapy with immunoglobulins,
intravenous steroids (dexamethasone), cyclosporine, and etoposide was performed …