The biology and treatment of plasmablastic lymphoma

JJ Castillo, M Bibas, RN Miranda - Blood, The Journal of the …, 2015 - ashpublications.org
Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV
infection. However, PBL can also be seen in patients with other immunodeficiencies as well …

Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification

G Ott, A Rosenwald, E Campo - Blood, The Journal of the …, 2013 - ashpublications.org
MYC is a potent oncogene initially identified as the target of the t (8; 14)(q24; q32)
chromosome translocation in Burkitt lymphoma. MYC gene alterations have been identified …

Co-infections, inflammation and oncogenesis: future directions for EBV research

AB Rickinson - Seminars in cancer biology, 2014 - Elsevier
Epstein–Barr virus (EBV) is aetiologically linked to a wide range of human tumours. Some
arise as accidents of the virus' lifestyle in its natural niche, the B lymphoid system; these …

Plasmablastic lymphoma: current perspectives

A Lopez, P Abrisqueta - Blood and lymphatic cancer: targets and …, 2018 - Taylor & Francis
Plasmablastic lymphoma (PbL) is a rare and aggressive B-cell malignancy with large
neoplastic cells, most of them resembling plasmablasts that have a CD20-negative …

Plasmablastic lymphoma: An update

J Bailly, N Jenkins, D Chetty… - International Journal …, 2022 - Wiley Online Library
Plasmablastic lymphoma (PBL) is a highly aggressive B cell non‐Hodgkin lymphoma
frequently associated with immunosuppression, particularly human immunodeficiency virus …

Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma

F Frontzek, AM Staiger, M Zapukhlyak, W Xu… - Nature …, 2021 - nature.com
Plasmablastic lymphoma (PBL) represents a rare and aggressive lymphoma subtype
frequently associated with immunosuppression. Clinically, patients with PBL are …

[HTML][HTML] Clinical characteristics and prognostic factors of plasmablastic lymphoma patients: analysis of 135 patients from the LYSA group

E Tchernonog, P Faurie, P Coppo, H Monjanel… - Annals of …, 2017 - Elsevier
Background Plasmablastic lymphoma (PBL), initially described in 1997 in the oral cavity of
HIV positive patients, is now recognized as a distinct aggressive and rare entity of diffuse …

Diagnosis and management of lymphomas and other cancers in HIV-infected patients

A Carbone, E Vaccher, A Gloghini… - Nature reviews Clinical …, 2014 - nature.com
Despite the introduction of highly active antiretroviral therapy or combination antiretroviral
therapy (HAART and cART, respectively) patients infected with HIV might develop certain …

[HTML][HTML] HIV and lymphoma: from epidemiology to clinical management

A Re, C Cattaneo, G Rossi - Mediterranean journal of hematology …, 2019 - ncbi.nlm.nih.gov
Patients infected with human immunodeficiency virus (HIV) are at increased risk for
developing both non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL). Even if this …

Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients

S Loghavi, K Alayed, TN Aladily, Z Zuo, SB Ng… - Journal of hematology & …, 2015 - Springer
Background Plasmablastic lymphoma (PBL) is a rare aggressive neoplasm with lymphoid
and plasmacytic differentiation that is commonly associated with immunodeficiency and an …