Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Acoustic behavior of microbubbles and implications for drug delivery

K Kooiman, HJ Vos, M Versluis, N De Jong - Advanced drug delivery …, 2014 - Elsevier
Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Bubble puzzles: from fundamentals to applications

D Lohse - Physical review fluids, 2018 - APS
For centuries, bubbles have fascinated artists, engineers, and scientists alike. In spite of
century-long research on them, new and often surprising bubble phenomena, features, and …

[HTML][HTML] Measuring cavitation and its cleaning effect

B Verhaagen, DF Rivas - Ultrasonics sonochemistry, 2016 - Elsevier
The advantages and limitations of techniques for measuring the presence and amount of
cavitation, and for quantifying the removal of contaminants, are provided. After reviewing …

Acoustic droplet vaporization is initiated by superharmonic focusing

O Shpak, M Verweij, HJ Vos… - Proceedings of the …, 2014 - National Acad Sciences
Acoustically sensitive emulsion droplets composed of a liquid perfluorocarbon have the
potential to be a highly efficient system for local drug delivery, embolotherapy, or for tumor …

High-speed imaging in fluids

M Versluis - Experiments in fluids, 2013 - Springer
High-speed imaging is in popular demand for a broad range of experiments in fluids. It
allows for a detailed visualization of the event under study by acquiring a series of image …

Giant and explosive plasmonic bubbles by delayed nucleation

Y Wang, ME Zaytsev, G Lajoinie… - Proceedings of the …, 2018 - National Acad Sciences
When illuminated by a laser, plasmonic nanoparticles immersed in water can very quickly
and strongly heat up, leading to the nucleation of so-called plasmonic vapor bubbles. While …

[HTML][HTML] The influence of inter-bubble spacing on the resonance response of ultrasound contrast agent microbubbles

H Yusefi, B Helfield - Ultrasonics Sonochemistry, 2022 - Elsevier
Ultrasound-driven microbubbles, typically between 1 and 8 µm in diameter, are resonant
scatterers that are employed as diagnostic contrast agents and emerging as potentiators of …

Viability of endothelial cells after ultrasound-mediated sonoporation: Influence of targeting, oscillation, and displacement of microbubbles

T van Rooij, I Skachkov, I Beekers, KR Lattwein… - Journal of Controlled …, 2016 - Elsevier
Microbubbles (MBs) have been shown to create transient or lethal pores in cell membranes
under the influence of ultrasound, known as ultrasound-mediated sonoporation. Several …