Chemical elicitors versus secondary metabolite production in vitro using plant cell, tissue and organ cultures: recent trends and a sky eye view appraisal

CC Giri, M Zaheer - Plant Cell, Tissue and Organ Culture (PCTOC), 2016 - Springer
Plant secondary biosynthetic pathways are exceedingly inducible by elicitors and facilitate
enhanced metabolite production using plant cell tissue and organ cultures. Elicitors can …

Endophytic fungi: novel sources of anticancer lead molecules

S Chandra - Applied microbiology and biotechnology, 2012 - Springer
Cancer is a major killer disease all over the world and more than six million new cases are
reported every year. Nature is an attractive source of new therapeutic compounds, as a …

Agrobacterium rhizogenes: recent developments and promising applications

V Veena, CG Taylor - In Vitro Cellular & Developmental Biology-Plant, 2007 - Springer
Agrobacterium rhizogenes is the etiological agent for hairy-root disease (also known as root-
mat disease). This bacterium induces the neoplastic growth of plant cells that differentiate to …

Hairy root culture an alternative for bioactive compound production from medicinal plants

A Roy - Current pharmaceutical biotechnology, 2021 - ingentaconnect.com
Medicinal plants produce a diverse group of phytocompounds like anthraquinones,
alkaloids, anthocyanins, flavonoids, saponins, and terpenes which are used in …

Lignans in plant cell and organ cultures: an overview

E Fuss - Phytochemistry Reviews, 2003 - Springer
Lignans are found in a wide variety of plant species. The lignan podophyllotoxin is of special
interest, since its derivatives like eg etopophos® are used in anticancer therapy. As …

Biotechnological aspects of the production of the anticancer drug podophyllotoxin

S Farkya, VS Bisaria, AK Srivastava - Applied microbiology and …, 2004 - Springer
The natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties
which occurs in a few plant species, is a pharmacologically important compound for its …

Agrobacterium rhizogenes mediated hairy root induction in endangered Berberis aristata DC.

L Brijwal, S Tamta - SpringerPlus, 2015 - Springer
An efficient protocol for hairy root induction in Berberis aristata DC. was established using
two different strains of Agrobacterium rhizogenes, MTCC 532 and 2364 from IMTECH …

Biotechnological approaches for production of anti-cancerous compounds resveratrol, podophyllotoxin and zerumbone

K Nandagopal, M Halder, B Dash… - Current Medicinal …, 2018 - ingentaconnect.com
Secondary metabolites from numerous plant sources have been developed as anti-cancer
reagents and compounds such as resveratrol, podophyllotoxin and zerumbone are of …

Biotechnological interventions for harnessing podophyllotoxin from plant and fungal species: current status, challenges, and opportunities for its commercialization

A Kumari, D Singh, S Kumar - Critical reviews in biotechnology, 2017 - Taylor & Francis
Podophyllotoxin is an aryltetralin lignan synthesized in several plant species, which is used
in chemotherapies for cancers and tumor treatment. More potent semisynthetic derivatives of …

Agrobacterium rhizogenes-Mediated Transformation and Its Biotechnological Applications in Crops

II Ozyigit, I Dogan, E Artam Tarhan - Crop improvement: new approaches …, 2013 - Springer
The history of Agrobacterium-related plant biotechnology goes back for more than three
decades with the discovery of molecular mechanisms of crown gall disease in plants. After …