Mechanisms and pathogenesis of chronic rhinosinusitis
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local
inflammation of the upper airways and is historically divided into 2 main phenotypes: CRS …
inflammation of the upper airways and is historically divided into 2 main phenotypes: CRS …
The role of small extracellular vesicles and MicroRNAs in the diagnosis and treatment of allergic rhinitis and nasal polyps
Y Liu, J Sha, C Meng, D Zhu - Mediators of Inflammation, 2022 - Wiley Online Library
Allergic rhinitis and nasal polyps are common otorhinolaryngological diseases. Small
extracellular vesicles and microRNAs have recently become major research topics of …
extracellular vesicles and microRNAs have recently become major research topics of …
Topical administration of verapamil in poly (ethylene glycol)-modified liposomes for enhanced sinonasal tissue residence in chronic rhinosinusitis: ex vivo and in vivo …
Verapamil is a calcium channel blocker that holds promise for the therapy of chronic
rhinosinusitis (CRS) with and without nasal polyps. The verapamil-induced side effects limit …
rhinosinusitis (CRS) with and without nasal polyps. The verapamil-induced side effects limit …
Hypoxia-inducible factor 1α activates the NLRP3 inflammasome to regulate epithelial differentiation in chronic rhinosinusitis
B Zhong, S Sun, KS Tan, HH Ong, J Du, F Liu… - Journal of Allergy and …, 2023 - Elsevier
Background Chronic rhinosinusitis (CRS) is an upper airway inflammation disease
associated with hypoxia-mediated inflammation. The effect of hypoxia-inducible factor 1α …
associated with hypoxia-mediated inflammation. The effect of hypoxia-inducible factor 1α …
Nanotechnology-enabled topical delivery of therapeutics in chronic rhinosinusitis
Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the paranasal sinuses
which represents a significant health burden due to its widespread prevalence and impact …
which represents a significant health burden due to its widespread prevalence and impact …
Roles of exosomes in chronic rhinosinusitis: a systematic review
K Dżaman, K Czerwaty - International journal of molecular sciences, 2022 - mdpi.com
The pathophysiology of chronic rhinosinusitis (CRS) is multifactorial and not entirely clear.
The objective of the review was to examine the current state of knowledge concerning the …
The objective of the review was to examine the current state of knowledge concerning the …
[HTML][HTML] Studies on absorption mechanism and pharmacokinetic properties of albendazole-bile acid conjugate: In vivo and in vitro
Z Guo, S Tang, K Nie, J Liu, C Hu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Purpose To improve the oral bioavailability of albendazole (ABZ), a series of albendazole-
bile acid conjugates (ABCs) were synthesized. ABC's transmembrane transport mechanism …
bile acid conjugates (ABCs) were synthesized. ABC's transmembrane transport mechanism …
Potential pharmacokinetic effect of chicken xenobiotic receptor activator on sulfadiazine: involvement of P-glycoprotein induction
M Li, Z Xu, W Lu, L Wang, Y Zhang - Antibiotics, 2022 - mdpi.com
Studies on pharmacokinetic drug–drug interactions have highlighted the importance of P-
glycoprotein (P-gp) because of its involvement in substrate drug transport. This study aimed …
glycoprotein (P-gp) because of its involvement in substrate drug transport. This study aimed …
[PDF][PDF] Outcome measures for chronic rhinosinusitis with nasal polyps
AR Sedaghat, RG Campbell, RG Douglas… - …, 2024 - researchgate.net
Background: With the recent proliferation of novel therapeutics for chronic rhinosinusitis with
nasal polyps (CRSwNP), there is an immediate need for comprehensive means to assess …
nasal polyps (CRSwNP), there is an immediate need for comprehensive means to assess …
糖皮质激素抵抗在耳鼻咽喉疾病中的研究进展
李亚秀， 佘万东 - 临床耳鼻咽喉头颈外科杂志, 2024 - lceh.whuhzzs.com
糖皮质激素(glucocorticoids, GC) 临床上广泛应用于自身免疫性内耳病, 突发性聋,
梅尼埃病及鼻窦炎等耳鼻咽喉疾病的治疗, 部分患者存在GC 抵抗现象, 但导致GC …
梅尼埃病及鼻窦炎等耳鼻咽喉疾病的治疗, 部分患者存在GC 抵抗现象, 但导致GC …