Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …

Tissue damage resulting from chemical, mechanical, and biological injury, or from
interrupted blood flow and reperfusion, is often life threatening. The subsequent tissue …

The worldwide prevalence of diabetes mellitus and obesity is rapidly increasing not only in
adults but also in children and adolescents. Diabetes is associated with macrovascular …

Objectives Peroxisome proliferator-activated receptors (PPAR) α and β/δ are essential
transcriptional regulators of fatty acid oxidation in the heart. However, little is known about …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear
transcription factors that belong to the nuclear receptor superfamily. Three isoforms of PPAR …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors that belong to the nuclear hormone receptor superfamily. The activation of PPAR …

Peroxisome proliferator-activated receptors (PPARs) are ligand dependent transcription
factors. The three mammalian PPARs are key regulators of fatty acid and lipoprotein …

Ischemia-reperfusion injury (IRI) is a complex pathophysiological process that is often
characterized as a blood circulation disorder caused due to various factors (such as …

Lovastatin (an HMG‐CoA reductase inhibitor) and troglitazone (a PPAR‐γ agonist) have
been intensively studied prospectively for their application in cancer treatment. However …

Objective: Here we investigate the effects of the endogenous prostaglandin D2 metabolite
15-deoxy-Δ12, 14-prostaglandin J2, on the renal dysfunction and injury caused by …