Current and Emerging Diagnostic, Prognostic, and Predictive Biomarkers in Head and Neck Cancer

HW Eberly, BY Sciscent, FJ Lorenz, EM Rettig, N Goyal - Biomedicines, 2024 - mdpi.com
Head and neck cancers (HNC) are a biologically diverse set of cancers that are responsible
for over 660,000 new diagnoses each year. Current therapies for HNC require a …

[HTML][HTML] The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer

A Krsek, L Baticic, T Braut, V Sotosek - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma
(HNSCC), particularly oropharyngeal squamous cell carcinoma (OPSCC), is an increasingly …

Detection of serum biomarkers of HPV-16 driven oropharynx and oral cavity cancer in Brazil

L Sichero, MG Gonçalves, F Bettoni, EM Coser, G Mota… - Oral Oncology, 2024 - Elsevier
Background HPV-16 driven oropharynx/oral cavity squamous cell carcinomas prevalence
varies globally. We evaluated the presence of HPV-16 ctDNA and HPV-16 E6 antibodies in …

[HTML][HTML] Blood-based screening for HPV-associated cancers

D Das, S Hirayama, L Aye, ME Bryan, S Naegele… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background: HPV-associated oropharyngeal cancer (HPV+ OPSCC) is the most common
HPV-associated cancer in the United States yet unlike cervical cancer lacks a screening test …

Assessing the feasibility of a multimodal liquid biopsy for the diagnosis of HPV-associated oropharyngeal squamous cell carcinoma

JS Lewis Jr, S Naegele, V Efthymiou… - American Journal of …, 2024 - academic.oup.com
Objectives In this feasibility study, we explored the combined use of circulating tumor human
papillomavirus (HPV) DNA (ctHPVDNA) and HPV serology as diagnostic tests for HPV …

[HTML][HTML] Molecular Mechanisms and Diagnostic Innovations in HPV-Associated Head and Neck Squamous Cell Carcinomas: Insights into Integration, Epigenetic …

G Shanmugam, G Jeyaraj, K Sarkar - Oral Oncology Reports, 2024 - Elsevier
Human papillomavirus (HPV) is a major etiological factor for head and neck cancers,
particularly in the oropharyngeal region, which includes the tonsils and base of the tongue …