Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening

RD Brown, JP Broderick - The Lancet Neurology, 2014 - thelancet.com
Intracranial saccular or berry aneurysms are common, occurring in about 1–2% of the
population. Unruptured intracranial aneurysms are increasingly being detected as cross …

Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association …

BG Thompson, RD Brown Jr, S Amin-Hanjani… - Stroke, 2015 - Am Heart Assoc
Purpose—The aim of this updated statement is to provide comprehensive and evidence-
based recommendations for management of patients with unruptured intracranial …

Vasospasm in cerebral inflammation

M Eisenhut - International journal of inflammation, 2014 - Wiley Online Library
All forms of cerebral inflammation as found in bacterial meningitis, cerebral malaria, brain
injury, and subarachnoid haemorrhage have been associated with vasospasm of cerebral …

Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms

T Aoki, J Frȍsen, M Fukuda, K Bando, G Shioi… - Science …, 2017 - science.org
Intracranial aneurysms are common but are generally untreated, and their rupture can lead
to subarachnoid hemorrhage. Because of the poor prognosis associated with subarachnoid …

The role of platelet activation and inflammation in early brain injury following subarachnoid hemorrhage

JA Frontera, JJ Provencio, FA Sehba, TM McIntyre… - Neurocritical care, 2017 - Springer
Background Early brain injury (EBI) following aneurysmal subarachnoid hemorrhage (SAH)
is an important predictor of poor functional outcome, yet the underlying mechanism is not …

Intracranial aneurysm as a macrophage-mediated inflammatory disease

K Shimizu, M Kushamae, T Mizutani… - Neurologia medico …, 2019 - jstage.jst.go.jp
Subarachnoid hemorrhage (SAH) is mainly attributable to the rupture of intracranial
aneurysms (IAs). Although the outcome of SAH is considerably poor in spite of the recent …

Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: a case-control study

A Can, RF Rudy, VM Castro, S Yu, D Dligach, S Finan… - Neurology, 2018 - AAN Enterprises
Objective To determine the association between ruptured saccular aneurysms and aspirin
use/aspirin dose. Methods Four thousand seven hundred one patients who were diagnosed …

Incidence and case fatality of aneurysmal subarachnoid hemorrhage admitted to hospital between 2008 and 2014 in Norway

LR Øie, O Solheim, P Majewska, T Nordseth… - Acta …, 2020 - Springer
Background To provide age-and sex-specific incidence and case fatality rates for non-
traumatic aneurysmal subarachnoid hemorrhage (aSAH) in Norway. We also studied time …

Characteristics of Unruptured compared to ruptured intracranial aneurysms: a multicenter case–control study

IC Hostettler, VS Alg, N Shahi, F Jichi, S Bonner… - …, 2018 - journals.lww.com
OBJECTIVE To test the hypothesis that unruptured aneurysms have different characteristics
and risk factor profiles compared to ruptured aneurysms. METHODS We recruited patients …

Prospective randomized open-label trial to evaluate risk factor management in patients with unruptured intracranial aneurysms: study protocol

MDI Vergouwen, GJE Rinkel, A Algra… - … Journal of Stroke, 2018 - journals.sagepub.com
Rationale Unruptured intracranial aneurysms are currently left untreated if the presumed
complication risk of preventive endovascular or neurosurgical intervention is higher than the …