Understanding inbreeding depression, purging, and genetic rescue
PW Hedrick, A Garcia-Dorado - Trends in ecology & evolution, 2016 - cell.com
Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal
phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates …
phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates …
Inbreeding depression due to recent and ancient inbreeding in Dutch Holstein–Friesian dairy cattle
Background Inbreeding decreases animal performance (inbreeding depression), but not all
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …
Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load
Inbreeding depression, the deterioration in mean trait value in progeny of related parents, is
a fundamental quantity in genetics, evolutionary biology, animal and plant breeding, and …
a fundamental quantity in genetics, evolutionary biology, animal and plant breeding, and …
Characterizing and Eliminating the Inbreeding Load
I Nagy, TA Nguyen - Veterinary Sciences, 2023 - mdpi.com
Simple Summary Inbreeding, which is the mating of related animals, is a general
phenomenon in closed populations. Because it is often associated with a decrease in …
phenomenon in closed populations. Because it is often associated with a decrease in …
Long-term exhaustion of the inbreeding load in Drosophila melanogaster
N Pérez-Pereira, R Pouso, A Rus, A Vilas… - Heredity, 2021 - nature.com
Inbreeding depression, the decline in fitness of inbred individuals, is a ubiquitous
phenomenon of great relevance in evolutionary biology and in the fields of animal and plant …
phenomenon of great relevance in evolutionary biology and in the fields of animal and plant …
Revised calculation of Kalinowski's ancestral and new inbreeding coefficients
To test for the presence of purging in populations, the classical pedigree-based inbreeding
coefficient (F) can be decomposed into Kalinowski's ancestral (FANC) and new (FNEW) …
coefficient (F) can be decomposed into Kalinowski's ancestral (FANC) and new (FNEW) …
Prediction of fitness under different breeding designs in conservation programs
N Pérez‐Pereira, E López‐Cortegano… - Animal …, 2023 - Wiley Online Library
The expected change in fitness under inbreeding due to deleterious recessive alleles
depends on the amount of inbreeding load harbored by a population, that is, the load of …
depends on the amount of inbreeding load harbored by a population, that is, the load of …
Inbreeding load and inbreeding depression estimated from lifetime reproductive success in a small, dispersal-limited population
The fitness consequences of inbreeding and the individual behaviors that prevent its
detrimental effects can be challenging to document in wild populations. Here, we use field …
detrimental effects can be challenging to document in wild populations. Here, we use field …
Genetic purging in captive endangered ungulates with extremely low effective population sizes
Inbreeding threatens the survival of small populations by producing inbreeding depression,
but also exposes recessive deleterious effects in homozygosis allowing for genetic purging …
but also exposes recessive deleterious effects in homozygosis allowing for genetic purging …
purgeR: inbreeding and purging in pedigreed populations
E López-Cortegano - Bioinformatics, 2022 - academic.oup.com
Inbreeding depression and genetic purging are important processes shaping the
survivability and evolution of small populations. However, detecting purging is challenging …
survivability and evolution of small populations. However, detecting purging is challenging …