Epitope mapping of polyclonal antibodies by hydrogen–deuterium exchange mass spectrometry (HDX-MS)
S Stander, L R. Grauslund, M Scarselli… - Analytical …, 2021 - ACS Publications
Epitope mapping of antibodies (Abs) is crucial for understanding adaptive immunity, as well
as studying the mode of action of therapeutic antibodies and vaccines. Especially insights …
as studying the mode of action of therapeutic antibodies and vaccines. Especially insights …
[HTML][HTML] Self-assembling protein nanoparticles and virus like particles correctly display β-barrel from meningococcal factor H-binding protein through genetic fusion
L Cappelli, P Cinelli, F Giusti, I Ferlenghi… - PLoS …, 2022 - journals.plos.org
Recombinant protein-based vaccines are a valid and safer alternative to traditional vaccines
based on live-attenuated or killed pathogens. However, the immune response of subunit …
based on live-attenuated or killed pathogens. However, the immune response of subunit …
Outer membrane protein OMP76 of Riemerella anatipestifer contributes to complement evasion and virulence by binding to duck complement factor vitronectin
S Li, Y Wang, R Yang, X Zhu, H Bai, X Deng, J Bai… - Virulence, 2023 - Taylor & Francis
Riemerella anatipestifer is an important bacterial pathogen in poultry. Pathogenic bacteria
recruit host complement factors to resist the bactericidal effect of serum complement …
recruit host complement factors to resist the bactericidal effect of serum complement …
Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H
D Veggi, CC Chesterman, L Santini… - FASEB …, 2024 - Wiley Online Library
Thousands of disease cases and hundreds of deaths occur globally each year due to
invasive meningococcal disease. Neisseria meningitidis serogroup B (MenB) is the leading …
invasive meningococcal disease. Neisseria meningitidis serogroup B (MenB) is the leading …
[HTML][HTML] Bioinformatics Analysis of Global Diversity in Meningococcal Vaccine Antigens over the Past 10 Years: Vaccine Efficacy Prognosis
VY Savitskaya, NG Dolinnaya, VV Strekalovskikh… - Medical …, 2023 - mdpi.com
Neisseria meningitidis (N. meningitidis) serogroup B (MenB) is the leading cause of invasive
meningococcal disease worldwide. The pathogen has a wide range of virulence factors …
meningococcal disease worldwide. The pathogen has a wide range of virulence factors …
[HTML][HTML] Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site
NA Sands, PT Beernink - PLoS Pathogens, 2021 - journals.plos.org
Microbial pathogens bind host complement regulatory proteins to evade the immune system.
The bacterial pathogen Neisseria meningitidis, or meningococcus, binds several …
The bacterial pathogen Neisseria meningitidis, or meningococcus, binds several …
[HTML][HTML] Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096
D Veggi, E Malito, PL Surdo, W Pansegrau… - Computational and …, 2022 - Elsevier
Invasive meningococcal disease can cause fatal sepsis and meningitis and is a global
health threat. Factor H binding protein (fHbp) is a protective antigen included in the two …
health threat. Factor H binding protein (fHbp) is a protective antigen included in the two …