Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1
Chromatin inheritance entails de novo nucleosome assembly after DNA replication by
chromatin assembly factor-1 (CAF-1). Yet direct knowledge about CAF-1's histone binding …
chromatin assembly factor-1 (CAF-1). Yet direct knowledge about CAF-1's histone binding …
Structural transition of the nucleosome during transcription elongation
T Kujirai, H Ehara, S Sekine, H Kurumizaka - Cells, 2023 - mdpi.com
In eukaryotes, genomic DNA is tightly wrapped in chromatin. The nucleosome is a basic unit
of chromatin, but acts as a barrier to transcription. To overcome this impediment, the RNA …
of chromatin, but acts as a barrier to transcription. To overcome this impediment, the RNA …
Are extraordinary nucleosome structures more ordinary than we thought?
CYY Chong, L Gan - Chromosoma, 2023 - Springer
The nucleosome is a DNA–protein assembly that is the basic unit of chromatin. A
nucleosome can adopt various structures. In the canonical nucleosome structure, 145–147 …
nucleosome can adopt various structures. In the canonical nucleosome structure, 145–147 …
Structural and dynamical investigation of histone H2B in well-hydrated nucleosome core particles by solid-state NMR
Abstract H2A-H2B dimer is a key component of nucleosomes and an important player in
chromatin biology. Here, we characterized the structure and dynamics of H2B in precipitated …
chromatin biology. Here, we characterized the structure and dynamics of H2B in precipitated …
Molecular dynamics simulations of nucleosomes are coming of age
AS Fedulova, GA Armeev… - Wiley …, 2024 - Wiley Online Library
Understanding the function of eukaryotic genomes, including the human genome, is
undoubtedly one of the major scientific challenges of the 21st century. The cornerstone of …
undoubtedly one of the major scientific challenges of the 21st century. The cornerstone of …
In Vivo Proximity Cross-Linking and Immunoprecipitation of Cell Wall Epitopes Identify Proteins Associated with the Biosynthesis of Matrix Polysaccharides
P Wannitikul, I Dachphun, J Sakulkoo… - ACS …, 2024 - ACS Publications
Identification of proteins involved in cell wall matrix polysaccharide biosynthesis is crucial to
understand plant cell wall biology. We utilized in vivo cross-linking and immunoprecipitation …
understand plant cell wall biology. We utilized in vivo cross-linking and immunoprecipitation …
Beyond the Usual Suspects: Examining the Role of Understudied Histone Variants in Breast Cancer
H Dhahri, WN Saintilnord, D Chandler… - International Journal of …, 2024 - mdpi.com
The incorporation of histone variants has structural ramifications on nucleosome dynamics
and stability. Due to their unique sequences, histone variants can alter histone–histone or …
and stability. Due to their unique sequences, histone variants can alter histone–histone or …
Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT
M Engeholm, JJ Roske, E Oberbeckmann… - Molecular Cell, 2024 - cell.com
To maintain the nucleosome organization of transcribed genes, ATP-dependent chromatin
remodelers collaborate with histone chaperones. Here, we show that at the 5′ ends of …
remodelers collaborate with histone chaperones. Here, we show that at the 5′ ends of …