[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism
T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
The SLC39 family of zinc transporters
J Jeong, DJ Eide - Molecular aspects of medicine, 2013 - Elsevier
Zinc is a trace element nutrient that is essential for life. This mineral serves as a cofactor for
enzymes that are involved in critical biochemical processes and it plays many structural …
enzymes that are involved in critical biochemical processes and it plays many structural …
Targeting EMT in cancer: opportunities for pharmacological intervention
The spread of cancer cells to distant organs represents a major clinical challenge in the
treatment of cancer. Epithelial–mesenchymal transition (EMT) has emerged as a key …
treatment of cancer. Epithelial–mesenchymal transition (EMT) has emerged as a key …
Gold nanoparticle–conjugated quercetin inhibits epithelial–mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR‐2‐mediated pathway in breast …
S Balakrishnan, FA Bhat, P Raja Singh… - Cell …, 2016 - Wiley Online Library
Objectives Epidermal growth factor plays a critical role in breast malignancies by enhancing
cell proliferation, invasion, angiogenesis and metastasis. Epithelial–mesenchymal transition …
cell proliferation, invasion, angiogenesis and metastasis. Epithelial–mesenchymal transition …
[HTML][HTML] Biomarkers in triple-negative breast cancer: state-of-the-art and future perspectives
S Cocco, M Piezzo, A Calabrese, D Cianniello… - International journal of …, 2020 - mdpi.com
Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors characterized by
aggressive behavior, high risk of distant recurrence, and poor survival. Chemotherapy is still …
aggressive behavior, high risk of distant recurrence, and poor survival. Chemotherapy is still …
Tracking and functional characterization of epithelial–mesenchymal transition and mesenchymal tumor cells during prostate cancer metastasis
M Ruscetti, B Quach, EL Dadashian, DJ Mulholland… - Cancer research, 2015 - AACR
The epithelial–mesenchymal transition (EMT) has been postulated as a mechanism by
which cancer cells acquire the invasive and stem-like traits necessary for distant metastasis …
which cancer cells acquire the invasive and stem-like traits necessary for distant metastasis …
[HTML][HTML] Gelatinase B/MMP-9 in tumour pathogenesis and progression
AR Farina, AR Mackay - Cancers, 2014 - mdpi.com
Since its original identification as a leukocyte gelatinase/type V collagenase and tumour
type IV collagenase, gelatinase B/matrix metalloproteinase (MMP)-9 is now recognised as …
type IV collagenase, gelatinase B/matrix metalloproteinase (MMP)-9 is now recognised as …
Toward unzipping the ZIP metal transporters: structure, evolution, and implications on drug discovery against cancer
J Hu - The FEBS journal, 2021 - Wiley Online Library
The Zrt‐/Irt‐like protein (ZIP) family consists of divalent metal transporters, ubiquitous in all
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …
[HTML][HTML] Particulate matter promotes cancer metastasis through increased HBEGF expression in macrophages
SH Park, SJ Yoon, S Choi, J Jung, JY Park… - … & molecular medicine, 2022 - nature.com
Although many cohort studies have reported that long-term exposure to particulate matter
(PM) can cause lung cancer, the molecular mechanisms underlying the PM-induced …
(PM) can cause lung cancer, the molecular mechanisms underlying the PM-induced …
Zinc transporter proteins
AK Baltaci, K Yuce - Neurochemical research, 2018 - Springer
Zinc, which is involved in the structure of all enzyme classes, is a micro nutrient element and
necessary for growth and development. The ability of zinc to function without causing toxic …
necessary for growth and development. The ability of zinc to function without causing toxic …