Relaxin family peptides and their receptors
RAD Bathgate, ML Halls… - Physiological …, 2013 - journals.physiology.org
There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …
many roles in female and male reproduction, as a neuropeptide in the central nervous …
Relaxin's physiological roles and other diverse actions
OD Sherwood - Endocrine reviews, 2004 - academic.oup.com
Relaxin has vital physiological roles in pregnant rats, mice, and pigs. Relaxin promotes
growth and softening of the cervix, thus facilitating rapid delivery of live young. Relaxin also …
growth and softening of the cervix, thus facilitating rapid delivery of live young. Relaxin also …
Anti‐Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo
JC Liao, JS Deng, CS Chiu, WC Hou… - Evidence‐Based …, 2012 - Wiley Online Library
We have investigated the anti‐inflammatory effects of Cinnamomum cassia constituents
(cinnamic aldehyde, cinnamic alcohol, cinnamic acid, and coumarin) using …
(cinnamic aldehyde, cinnamic alcohol, cinnamic acid, and coumarin) using …
The effect of relaxin on the musculoskeletal system
Relaxin is a hormone structurally related to insulin and insulin‐like growth factor, which
exerts its regulatory effect on the musculoskeletal and other systems through binding to its …
exerts its regulatory effect on the musculoskeletal and other systems through binding to its …
Adipokines and inflammation: focus on cardiovascular diseases
S Feijóo-Bandín, A Aragón-Herrera… - International journal of …, 2020 - mdpi.com
It is well established that adipose tissue, apart from its energy storage function, acts as an
endocrine organ that produces and secretes a number of bioactive substances, including …
endocrine organ that produces and secretes a number of bioactive substances, including …
Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes
YC Shen, WF Chiou, YC Chou, CF Chen - European journal of …, 2003 - Elsevier
To evaluate the possible mechanisms responsible for the anti-inflammatory effects of
baicalin or baicalein, phorbol-12-myristate-13-acetate (PMA)-or N-formyl-methionyl-leucyl …
baicalin or baicalein, phorbol-12-myristate-13-acetate (PMA)-or N-formyl-methionyl-leucyl …
International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family …
ML Halls, RAD Bathgate, SW Sutton… - Pharmacological …, 2015 - Elsevier
Abstract Relaxin, insulin-like peptide 3 (INSL3), relaxin-3, and INSL5 are the cognate
ligands for the relaxin family peptide (RXFP) receptors 1–4, respectively. RXFP1 activates …
ligands for the relaxin family peptide (RXFP) receptors 1–4, respectively. RXFP1 activates …
Cardiovascular effects of relaxin: from basic science to clinical therapy
Although substantial advances have been achieved in recent decades in the clinical
management of heart diseases, new therapies that provide better or additional efficacy with …
management of heart diseases, new therapies that provide better or additional efficacy with …
The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production
KT Liou, YC Shen, CF Chen, CM Tsao… - European journal of …, 2003 - Elsevier
Reactive oxygen species produced by neutrophils contribute to the pathogenesis of focal
cerebral ischemia/reperfusion injury and signal the inflammatory response. We have …
cerebral ischemia/reperfusion injury and signal the inflammatory response. We have …
Reperfusion therapy with recombinant human relaxin-2 (Serelaxin) attenuates myocardial infarct size and NLRP3 inflammasome following ischemia/reperfusion injury …
J Valle Raleigh, AG Mauro… - Cardiovascular …, 2017 - academic.oup.com
Aims The preconditioning-like infarct-sparing and anti-inflammatory effects of the peptide
hormone relaxin following ischemic injury have been studied in the heart. Whether …
hormone relaxin following ischemic injury have been studied in the heart. Whether …